Q9C169

PR
Gene name
cat-3 (NCU00355)
Protein name
Catalase-3
Names
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU00355
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

11 structures for Q9C169

Entry ID Method Resolution Chain Position Source
3EJ6 X-ray 230 A A/B/C/D 32-719 PDB
3ZJ4 X-ray 310 A A/B/C/D 1-719 PDB
3ZJ5 X-ray 195 A A/B/C/D 1-719 PDB
4AJ9 X-ray 185 A A/B/C/D 38-719 PDB
4BIM X-ray 295 A A/B/C/D 1-719 PDB
6NSW X-ray 210 A A/B/C/D 1-719 PDB
6NSY X-ray 220 A A/B/C/D 1-719 PDB
6NSZ X-ray 220 A A/B/C/D 1-719 PDB
6NT0 X-ray 220 A A/B/C/D 1-719 PDB
6NT1 X-ray 220 A A/B/C/D 1-719 PDB
AF-Q9C169-F1 Predicted AlphaFoldDB

No variants for Q9C169

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9C169

No associated diseases with Q9C169

4 regional properties for Q9C169

Type Name Position InterPro Accession
domain Catalase immune-responsive domain 473 - 536 IPR010582
domain Catalase core domain 56 - 443 IPR011614
active_site Catalase active site 91 - 107 IPR024708
domain Large catalase, C-terminal domain 568 - 714 IPR041399

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRVNALLPLS GLIGTALAAC PFADPSALGR RAEGGEVDAR QRLKEVEVDD NGQFMTTDFG
70 80 90 100 110 120
GNIEEQFSLK AGGRGSTLLE DFIFRQKLQH FDHERIPERV VHARGAGAHG IFTSYGDWSN
130 140 150 160 170 180
ITAASFLGAK DKQTPVFVRF STVAGSRGSA DTARDVHGFA TRFYTDEGNF DIVGNNIPVF
190 200 210 220 230 240
FIQDAIRFPD LIHSVKPSPD NEVPQAATAH DSAWDFFSSQ PSALHTLFWA MSGNGIPRSY
250 260 270 280 290 300
RHMDGFGIHT FRLVTEDGKS KLVKWHWKTK QGKAALVWEE AQVLAGKNAD FHRQDLWDAI
310 320 330 340 350 360
ESGNAPSWEL AVQLIDEDKA QAYGFDLLDP TKFLPEEFAP LQVLGEMTLN RNPMNYFAET
370 380 390 400 410 420
EQISFQPGHI VRGVDFTEDP LLQGRLYSYL DTQLNRHRGP NFEQLPINRP VSGVHNNHRD
430 440 450 460 470 480
GQGQAWIHKN IHHYSPSYLN KGYPAQANQT VGRGFFTTPG RTASGVLNRE LSATFDDHYT
490 500 510 520 530 540
QPRLFFNSLT PVEQQFVINA IRFEASHVTN EQVKKNVLEQ LNKISNDVAK RVAVALGLEA
550 560 570 580 590 600
PQPDPTYYHN NVTRGVSIFN ESLPTIATLR VGVLSTTKGG SLDKAKALKE QLEKDGLKVT
610 620 630 640 650 660
VIAEYLASGV DQTYSAADAT AFDAVVVAEG AERVFSGKGA MSPLFPAGRP SQILTDGYRW
670 680 690 700 710
GKPVAAVGSA KKALQSIGVE EKEAGVYAGA QDEVIKGVEE GLKVFKFLER FAVDGDDEE