AiPD: Autoinhibited Protein Database

Q9BRP7

Gene name	FDXACB1
Protein name	Ferredoxin-fold anticodon-binding domain-containing protein 1
Names	FDX-ACDB domain-containing protein 1
Species	Homo sapiens (Human)
KEGG Pathway	hsa:91893
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

269-359 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

269-359 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9BRP7

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9BRP7-F1	Predicted				AlphaFoldDB

510 variants for Q9BRP7

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA382584816 rs782795404	2	A>P		No	ClinGen ExAC gnomAD
CA6275222 rs782795404	2	A>S		No	ClinGen ExAC gnomAD
CA382584813 rs1309809670	2	A>V		No	ClinGen TOPMed gnomAD
CA6275220 rs781928142	3	P>L		No	ClinGen ExAC gnomAD
rs781928142 CA382584808	3	P>R		No	ClinGen ExAC gnomAD
CA6275219 rs199757538	4	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA382584801 rs1555162702	5	R>C		No	ClinGen gnomAD
rs1555162701 CA382584800	5	R>H		No	ClinGen gnomAD
rs1555162701 CA382584797	5	R>L		No	ClinGen gnomAD
rs782085797 CA6275218	8	L>W		No	ClinGen ExAC TOPMed gnomAD
CA6275217 rs781982130	9	V>I		No	ClinGen ExAC gnomAD
CA382584770 rs1251927299	10	G>E		No	ClinGen TOPMed gnomAD
CA382584747 rs1470219054	12	G>A		No	ClinGen TOPMed gnomAD
rs1405125160 CA382584744	13	N>H		No	ClinGen TOPMed gnomAD
CA6275212 rs782228373	16	F>L		No	ClinGen ExAC gnomAD
rs1165550531 CA382584694	17	A>G		No	ClinGen TOPMed
CA382584698 rs1555162690	17	A>T		No	ClinGen gnomAD
rs1396503947 CA382584674	20	L>M		No	ClinGen TOPMed
CA382584617 rs1592492503	23	T>P		No	ClinGen Ensembl
rs782589397 CA6275211	24	L>P		No	ClinGen ExAC gnomAD
rs979760190 CA228527580	24	L>V		No	ClinGen gnomAD
rs952523075 CA228527576	25	D>H		No	ClinGen TOPMed
CA382584580 rs1555162681	26	Q>R		No	ClinGen gnomAD
rs531261233 CA228527575	27	S>G		No	ClinGen 1000Genomes
rs782532363 CA382584567	27	S>R		No	ClinGen ExAC gnomAD
VAR_062165 rs59164893 CA6275209	28	T>A		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs972483329 CA228527560	28	T>I		No	ClinGen TOPMed gnomAD
rs782690801 CA382584545	29	Q>H		No	ClinGen ExAC gnomAD
CA6275207 rs782537413	30	L>F		No	ClinGen ExAC gnomAD
CA6275205 rs527479966	31	T>N		No	ClinGen 1000Genomes ExAC gnomAD
rs200945875 CA382584534	31	T>P		No	ClinGen 1000Genomes ExAC
rs200945875 CA6275206	31	T>S		No	ClinGen 1000Genomes ExAC
CA6275203 rs781827872	32	A>P		No	ClinGen ExAC gnomAD
CA382584512 rs1371245471	33	T>I		No	ClinGen TOPMed
CA6275202 rs782749583	33	T>P		No	ClinGen ExAC gnomAD
CA382584505 rs1228382030	34	C>F		No	ClinGen TOPMed gnomAD
rs1555162670 CA382584487	36	Q>K		No	ClinGen gnomAD
CA382584480 rs1555162669	36	Q>R		No	ClinGen gnomAD
CA382584471 rs1294440962	37	R>G		No	ClinGen TOPMed gnomAD
CA6275201 rs782157404	37	R>H		No	ClinGen ExAC TOPMed gnomAD
CA228527532 rs782157404	37	R>P		No	ClinGen ExAC TOPMed gnomAD
rs782008194 CA6275200	38	P>L		No	ClinGen ExAC gnomAD
CA382584401 rs200121963	40	E>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs782050794 CA6275198	40	E>G		No	ClinGen ExAC TOPMed gnomAD
CA382584386 rs1555162662	42	A>P		No	ClinGen gnomAD
CA6275194 rs201345383	43	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA382584376 rs201345383	43	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6275193 rs782418929	44	D>Y		No	ClinGen ExAC gnomAD
CA6275190 rs782445482	45	P>L		No	ClinGen ExAC TOPMed gnomAD
CA6275191 rs782578408	45	P>S		No	ClinGen ExAC gnomAD
CA6275188 rs577881821	46	L>P		No	ClinGen 1000Genomes ExAC gnomAD
CA6275189 rs782239827	46	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1482442130 CA382584340	47	A>V		No	ClinGen TOPMed
CA382584328 rs1419863509	48	W>*		No	ClinGen TOPMed gnomAD
rs1419863509 CA382584327	48	W>C		No	ClinGen TOPMed gnomAD
rs781895916 CA6275185	50	N>D		No	ClinGen ExAC TOPMed gnomAD
rs782440405 CA6275183	50	N>K		No	ClinGen ExAC gnomAD
rs368645940 CA6275184	50	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs782425968 CA6275182	52	Q>L		No	ClinGen ExAC TOPMed gnomAD
CA382584271 rs1555162641	53	C>F		No	ClinGen gnomAD
rs1172784358 CA382584278	53	C>R		No	ClinGen TOPMed
rs1555162641 CA382584273	53	C>S		No	ClinGen gnomAD
rs1555162641 CA382584274	53	C>Y		No	ClinGen gnomAD
CA6275180 rs782081440	55	R>P		No	ClinGen ExAC gnomAD
rs782767492 CA6275178	56	E>*		No	ClinGen ExAC TOPMed gnomAD
rs782169934 CA6275177	56	E>G		No	ClinGen ExAC gnomAD
CA6275179 rs782767492	56	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1555162627 CA382584241	57	R>G		No	ClinGen gnomAD
CA228527441 rs904559247	58	G>R		No	ClinGen TOPMed gnomAD
CA382584232 rs904559247	58	G>S		No	ClinGen TOPMed gnomAD
CA382583931 rs1411778026	60	D>N		No	ClinGen TOPMed gnomAD
CA6275146 rs201328668	61	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA6275143 rs374033566	62	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA6275142 rs374033566	62	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA6275141 rs370499813	62	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA382583913 rs370499813	62	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA6275144 rs374033566	62	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA382583902 rs1555162579	64	G>C		No	ClinGen gnomAD
CA382583866 rs1329001651	66	D>E		No	ClinGen TOPMed
rs782381416 CA6275139	67	C>F		No	ClinGen ExAC gnomAD
rs1337001085 CA382583845	68	T>I		No	ClinGen TOPMed gnomAD
rs782687266 CA6275137	69	Q>P		No	ClinGen ExAC gnomAD
rs968688606 CA228527216	71	A>V		No	ClinGen Ensembl
rs1021614224 CA228527212	75	E>G		No	ClinGen Ensembl
CA382583766 rs1555162574	75	E>Q		No	ClinGen gnomAD
CA6275134 rs140776979	76	L>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs782502997 CA6275133	77	H>L		No	ClinGen ExAC gnomAD
rs781828338 CA6275132	80	E>*		No	ClinGen ExAC TOPMed gnomAD
CA6275131 rs782797698	82	D>N		No	ClinGen ExAC gnomAD
CA228527202 rs782115847	83	Q>*		No	ClinGen ExAC TOPMed gnomAD
CA382583687 rs1555162568	83	Q>H		No	ClinGen gnomAD
CA6275130 rs782115847	83	Q>K		No	ClinGen ExAC TOPMed gnomAD
rs781882088 CA6275129	86	F>V		No	ClinGen ExAC gnomAD
CA6275128 VAR_060321 rs611010	87	I>N		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA382583659 rs611010	87	I>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs611010 CA382583660	87	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA382583649 rs1180655775	89	P>S		No	ClinGen TOPMed gnomAD
rs376916792 CA6275127	90	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA6275126 rs781966023	91	C>Y		No	ClinGen ExAC gnomAD
rs1003034139 CA228527153	92	G>A		No	ClinGen Ensembl
CA6275125 rs782336577	94	K>Q		No	ClinGen ExAC gnomAD
CA382583599 rs1555162550	97	V>I		No	ClinGen gnomAD
CA382583589 rs1555162545	98	A>G		No	ClinGen gnomAD
rs373717788 CA6275123	99	K>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA228527141 rs369672818	99	K>T		No	ClinGen ESP TOPMed
CA6275122 rs377284681	100	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs782282773 CA6275121	102	E>V		No	ClinGen ExAC gnomAD
COSM4145306 rs144833582 CA6275108 COSM4145305	114	V>I	thyroid [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA382583452 rs1207203640	116	A>V		No	ClinGen TOPMed gnomAD
rs1249355458 CA382583449	117	E>K		No	ClinGen TOPMed
rs1555162286 CA382583443	118	E>K		No	ClinGen gnomAD
CA6275105 rs372496285	121	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA382583412 rs1555162280	122	H>R		No	ClinGen gnomAD
CA382583408 rs370171096	123	V>L		No	ClinGen ESP ExAC gnomAD
CA6275103 rs370171096	123	V>M		No	ClinGen ESP ExAC gnomAD
CA6275102 rs782021417	124	A>E		No	ClinGen ExAC gnomAD
CA382583401 rs1555162274	124	A>S		No	ClinGen gnomAD
rs183279459 CA6275100	127	R>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
COSM1197220 rs200459403 CA6275099 COSM1197219	130	G>D	lung [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs1592490027 CA382583361	130	G>S		No	ClinGen Ensembl
rs1555162267 CA382583341	133	P>L		No	ClinGen gnomAD
rs782349669 CA382583337	134	A>E		No	ClinGen ExAC TOPMed gnomAD
rs782349669 CA6275098	134	A>V		No	ClinGen ExAC TOPMed gnomAD
rs781988715 CA6275096	135	D>G		No	ClinGen ExAC gnomAD
rs368204224 CA228526286	136	K>Q		No	ClinGen TOPMed
rs1592490002 CA382582734	137	P>L		No	ClinGen Ensembl
rs782439881 CA6275095	139	R>T		No	ClinGen ExAC gnomAD
CA228526276 rs782263609	140	E>K		No	ClinGen Ensembl
CA228526268 rs1044877088	141	W>R		No	ClinGen TOPMed gnomAD
rs1012502792 CA228526265	142	H>R		No	ClinGen Ensembl
CA382582639 rs1555162255	142	H>Y		No	ClinGen gnomAD
rs1555162253 CA382582595	144	S>R		No	ClinGen gnomAD
rs782211070 CA6275090	150	M>T		No	ClinGen ExAC TOPMed gnomAD
rs1555162248 CA382582489	150	M>V		No	ClinGen gnomAD
rs1555162245 CA382582462	151	A>S		No	ClinGen gnomAD
rs782647610 CA6275089	151	A>V		No	ClinGen ExAC gnomAD
CA382582448 rs1555162243	152	A>P		No	ClinGen gnomAD
rs1313823289 CA382582393	155	G>E		No	ClinGen TOPMed gnomAD
rs554893289 CA6275086	155	G>R		No	ClinGen 1000Genomes ExAC gnomAD
rs1313823289 CA382582387	155	G>V		No	ClinGen TOPMed gnomAD
CA382582396 rs554893289	155	G>W		No	ClinGen 1000Genomes ExAC gnomAD
CA6275082 rs781791480	156	L>H		No	ClinGen ExAC gnomAD
CA382582327 rs1272321186	159	S>G		No	ClinGen TOPMed
CA6275080 rs75258745	160	D>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs367952793 CA228526229	161	V>M		No	ClinGen ESP TOPMed gnomAD
CA6275077 rs782173873	162	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA6275076 rs782024980	163	P>A		No	ClinGen ExAC gnomAD
rs1566369235 CA382582274	163	P>L		No	ClinGen Ensembl
rs782300536 CA6275075	164	F>L		No	ClinGen ExAC
rs1555162228 CA382624572	169	V>E		No	ClinGen gnomAD
rs569000920 CA6275074	171	G>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA382624559 rs569000920	171	G>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1592489862 CA382624556	172	Y>D		No	ClinGen Ensembl
rs1555162225 CA382624544	173	K>N		No	ClinGen gnomAD
rs782385232 CA6275072	174	C>*		No	ClinGen ExAC gnomAD
CA382624539 rs1388814818	174	C>Y		No	ClinGen TOPMed gnomAD
rs782275453 CA228566505	175	T>A		No	ClinGen ExAC TOPMed gnomAD
rs782275453 CA6275071	175	T>P		No	ClinGen ExAC TOPMed gnomAD
rs782682396 CA6275070	175	T>S		No	ClinGen ExAC gnomAD
rs1555162220 CA382624529	176	G>V		No	ClinGen gnomAD
rs781984213 CA6275052	178	R>S		No	ClinGen ExAC
CA6275069 rs782535465	178	R>T		No	ClinGen ExAC gnomAD
CA6275051 rs782420239	180	Q>*		No	ClinGen ExAC gnomAD
rs782148977 CA6275050	180	Q>P		No	ClinGen ExAC gnomAD
rs1342645109 CA382624483	181	D>G		No	ClinGen TOPMed
CA382624485 rs1276483324	181	D>H		No	ClinGen TOPMed
rs1268496553 CA382624475	182	K>R		No	ClinGen TOPMed gnomAD
CA6275047 rs782227098	184	F>L		No	ClinGen ExAC gnomAD
rs1555162187 CA382624447	186	V>A		No	ClinGen gnomAD
CA6275046 rs782596239	186	V>L		No	ClinGen ExAC gnomAD
CA6275044 rs782246443	188	G>D		No	ClinGen ExAC TOPMed gnomAD
rs1555162184 CA382624432	189	A>T		No	ClinGen gnomAD
CA382624408 rs1555162183	192	H>R		No	ClinGen gnomAD
CA6275043 rs782689448	192	H>Y		No	ClinGen ExAC gnomAD
rs371392509 CA6275042	193	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6275041 rs530922734	195	T>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6275038 rs781866894	199	P>H		No	ClinGen ExAC TOPMed gnomAD
rs781866894 CA382624360	199	P>L		No	ClinGen ExAC TOPMed gnomAD
rs201248796 CA6275039	199	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs781881813 CA6275034	201	E>A		No	ClinGen ExAC TOPMed gnomAD
rs1555162173 CA382624341	202	G>D		No	ClinGen gnomAD
CA382624330 rs1325485447	204	Q>*		No	ClinGen TOPMed
rs1555162170 CA382624324	205	P>S		No	ClinGen gnomAD
rs1555162170 CA382624322	205	P>T		No	ClinGen gnomAD
CA382624311 rs1566368679	207	I>V		No	ClinGen Ensembl
CA6275031 rs781973551	212	L>P		No	ClinGen ExAC TOPMed gnomAD
CA382624244 rs868910425	216	W>*		No	ClinGen TOPMed
CA382624226 rs1352026796	218	S>F		No	ClinGen TOPMed
CA6275029 rs782347826	220	P>A		No	ClinGen ExAC TOPMed gnomAD
CA6275028 rs542018782	220	P>R		No	ClinGen 1000Genomes ExAC gnomAD
rs781990717 CA6275026	223	E>*		No	ClinGen ExAC TOPMed gnomAD
rs1004782244 CA228566266	223	E>G		No	ClinGen TOPMed gnomAD
rs782420720 CA6275025	224	A>V		No	ClinGen ExAC TOPMed gnomAD
CA6275024 rs782282119	225	L>P		No	ClinGen ExAC gnomAD
CA228566250 rs886368667	226	V>A		No	ClinGen TOPMed gnomAD
CA382624179 rs1292084661	226	V>L		No	ClinGen TOPMed
rs782592918 CA6275022	227	G>R		No	ClinGen ExAC gnomAD
rs1047021765 CA228566228	229	L>S		No	ClinGen TOPMed gnomAD
CA382624153 rs1566368541	230	N>S		No	ClinGen Ensembl
rs1555162160 CA382624149	231	R>G		No	ClinGen gnomAD
CA382624119 rs1188695306	232	G>V		No	ClinGen TOPMed
rs1555162127 CA382624085	236	A>P		No	ClinGen gnomAD
rs1555162127 CA382624084	236	A>T		No	ClinGen gnomAD
rs369039452 CA228566016	236	A>V		No	ClinGen ESP
CA6275007 rs781875795	237	P>T		No	ClinGen ExAC gnomAD
rs782764668 CA6275006	240	H>Y		No	ClinGen ExAC TOPMed gnomAD
CA228565991 rs142473337	242	I>V		No	ClinGen 1000Genomes TOPMed
rs375728601 CA228565971	243	K>N		No	ClinGen ESP
CA382624011 rs1566368148	243	K>R		No	ClinGen Ensembl
rs963165619 CA228565958	244	T>I		No	ClinGen TOPMed gnomAD
TCGA novel	249	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs782020485 CA6275003	251	A>V		No	ClinGen ExAC gnomAD
CA6275002 rs782736410	255	K>*		No	ClinGen ExAC gnomAD
rs1592489228 CA382623885	255	K>R		No	ClinGen Ensembl
rs1178891170 CA382623859	257	F>S		No	ClinGen TOPMed
rs189903941 CA6275000	258	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1364171010 CA382623809	259	L>P		No	ClinGen TOPMed gnomAD
CA382623807 rs1364171010	259	L>R		No	ClinGen TOPMed gnomAD
TCGA novel	261	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1555162107 CA382623757	261	R>S		No	ClinGen gnomAD
rs1381030608 CA382623720	263	K>T		No	ClinGen TOPMed
rs1332070975 CA382623688	264	C>S		No	ClinGen TOPMed
CA382623649 rs1555162095	266	Y>H		No	ClinGen gnomAD
rs1592489159 CA382623639	266	Y>S		No	ClinGen Ensembl
rs267602690 CA228565880	267	P>L		No	ClinGen Ensembl
rs782029467 CA6274995	267	P>S		No	ClinGen ExAC gnomAD
rs1555162089 CA382623582	269	L>P		No	ClinGen gnomAD
rs1225774726 CA382623562	270	P>L		No	ClinGen TOPMed
CA6274994 rs782400704	271	Q>*		No	ClinGen ExAC gnomAD
CA382623528 rs1261630681	272	E>K		No	ClinGen TOPMed
CA6274992 rs782559863	273	G>C		No	ClinGen ExAC gnomAD
CA382623480 rs1566367918	275	S>G		No	ClinGen Ensembl
rs557152920 CA6274991	276	V>I		No	ClinGen 1000Genomes ExAC TOPMed
rs782215561 CA6274990	277	L>I		No	ClinGen ExAC TOPMed gnomAD
CA6274989 rs201952370	278	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6274988 rs201952370	278	P>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1555162083 CA382623433	279	F>L		No	ClinGen gnomAD
CA382623346 rs1185883110	283	D>E		No	ClinGen TOPMed
CA6274987 rs781909860	283	D>V		No	ClinGen ExAC gnomAD
CA6274986 rs782812093	284	F>V		No	ClinGen ExAC TOPMed gnomAD
rs376903298 CA382623330	286	S>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs376903298 CA6274985	286	S>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs781795968 CA6274984	287	A>T		No	ClinGen ExAC gnomAD
CA382623317 rs1469546051	289	F>I		No	ClinGen TOPMed gnomAD
rs782714957 CA382623290	292	S>N		No	ClinGen ExAC TOPMed gnomAD
rs782714957 CA6274983	292	S>T		No	ClinGen ExAC TOPMed gnomAD
rs782127058 CA6274982	293	L>H		No	ClinGen ExAC gnomAD
CA382623274 rs1347058565	294	H>Q		No	ClinGen TOPMed
CA382623261 rs781976406	296	D>G		No	ClinGen ExAC TOPMed gnomAD
CA382623264 rs1555162074	296	D>H		No	ClinGen gnomAD
rs781976406 CA6274981	296	D>V		No	ClinGen ExAC TOPMed gnomAD
rs1555162073 CA382623255	297	N>S		No	ClinGen gnomAD
rs782147764 CA6274979	300	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6274980 rs782807549	300	S>T		No	ClinGen ExAC
rs1555162069 CA382623219	302	S>F		No	ClinGen gnomAD
CA6274976 rs782224550	304	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1555162066 CA382623190	305	G>D		No	ClinGen gnomAD
rs367754447 CA6274975	306	G>R		No	ClinGen ESP ExAC gnomAD
rs1407282129 CA382623145	309	Q>K		No	ClinGen TOPMed
rs374128358 CA228565760	309	Q>R		No	ClinGen ESP gnomAD
CA6274973 rs534644379	314	F>L		No	ClinGen 1000Genomes ExAC gnomAD
CA6274972 rs782250299	314	F>S		No	ClinGen ExAC gnomAD
rs371239584 CA6274971	315	L>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs371239584 CA382622998	315	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1314649956 CA382622947	317	S>A		No	ClinGen TOPMed gnomAD
rs1314649956 CA382622950	317	S>P		No	ClinGen TOPMed gnomAD
CA228565745 rs924214638	321	L>R		No	ClinGen Ensembl
rs782205189 CA6274969	323	L>F		No	ClinGen ExAC TOPMed gnomAD
CA6274967 rs782504862	327	P>L		No	ClinGen ExAC gnomAD
CA382622647 rs1555162049	328	G>E		No	ClinGen gnomAD
CA382622611 rs1489458854	330	D>N		No	ClinGen TOPMed
CA382622554 rs1220158440	331	G>D		No	ClinGen TOPMed
rs374384559 CA6274965	334	E>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs1555162040 CA382622379	337	E>*		No	ClinGen Ensembl
CA382622357 rs1555162039	338	G>*		No	ClinGen gnomAD
CA6274962 rs781886688	338	G>E		No	ClinGen ExAC gnomAD
CA6274960 rs370683740	339	T>I		No	ClinGen ESP ExAC gnomAD
rs370683740 CA6274959	339	T>N		No	ClinGen ESP ExAC gnomAD
CA6274961 rs782712776	339	T>S		No	ClinGen ExAC gnomAD
rs782721202 CA6274958	341	G>C		No	ClinGen ExAC gnomAD
rs376141657 CA6274957	341	G>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6274955 rs563448840	342	Q>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6274953 rs781943119	345	I>L		No	ClinGen ExAC gnomAD
rs1350536497 CA382622076	347	L>H		No	ClinGen TOPMed
TCGA novel	348	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6274951 rs782239950	349	P>S		No	ClinGen ExAC gnomAD
CA382621871 rs1555162029	354	H>P		No	ClinGen gnomAD
rs1555162026 CA382621852	355	V>A		No	ClinGen gnomAD
CA6274949 rs782363909	355	V>F		No	ClinGen ExAC gnomAD
TCGA novel	356	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1555162024 CA382621846	356	Q>E		No	ClinGen gnomAD
rs1301773130 TCGA novel CA382621833	357	D>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen TOPMed NCI-TCGA
rs372889858 CA6274947	357	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA6274945 rs782450166	359	I>F		No	ClinGen ExAC TOPMed
rs782450166 CA382621825	359	I>V		No	ClinGen ExAC TOPMed
CA6274942 rs782469814	360	E>D		No	ClinGen ExAC gnomAD
rs782617995 COSM923052 CA6274943 COSM923051	360	E>K	Variant assessed as Somatic; 4.641e-05 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs782617995 CA382621819	360	E>Q		No	ClinGen ExAC gnomAD
rs370579560 CA6274941	362	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1370790792 CA382621792	364	F>V		No	ClinGen TOPMed
rs782777581 CA6274940	368	S>C		No	ClinGen ExAC gnomAD
rs755792614 CA228565565	369	L>P		No	ClinGen Ensembl
rs782162578 CA6274939	370	H>R		No	ClinGen ExAC TOPMed gnomAD
CA382621746 rs1555162011	371	I>N		No	ClinGen gnomAD
rs781891264 CA6274938	373	S>G		No	ClinGen ExAC gnomAD
rs373040520 CA382621720	375	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA6274936 rs373040520	375	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA382621723 rs376322554	375	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA6274937 rs376322554	375	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA382621719 rs1483322771	376	V>I		No	ClinGen TOPMed
CA228565531 rs983243600	380	C>S		No	ClinGen Ensembl
CA382621680 rs1555162004	381	H>Y		No	ClinGen gnomAD
rs782353556 CA6274934	382	I>T		No	ClinGen ExAC TOPMed gnomAD
rs1555162002 CA382621662	383	L>F		No	ClinGen gnomAD
rs61739323 CA6274933	385	F>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6274931 rs782404074	387	M>V		No	ClinGen ExAC gnomAD
rs1566367100 CA382621623	389	A>V		No	ClinGen Ensembl
rs1555161993 CA382621610	391	H>R		No	ClinGen Ensembl
CA6274930 rs782188535	393	T>A		No	ClinGen ExAC gnomAD
rs781783782 CA6274928	393	T>I		No	ClinGen ExAC gnomAD
rs781783782 CA6274929	393	T>N		No	ClinGen ExAC gnomAD
CA382621598 rs782188535	393	T>P		No	ClinGen ExAC gnomAD
CA6274927 rs782212436	396	I>T		No	ClinGen ExAC TOPMed gnomAD
CA6274926 rs137921139	398	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs964676897 CA228565438	399	V>I		No	ClinGen TOPMed
rs1555161987 CA382621554	400	N>S		No	ClinGen gnomAD
CA6274924 rs782292027	401	Q>H		No	ClinGen ExAC gnomAD
TCGA novel	401	Q>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs782504201 CA6274925	401	Q>R		No	ClinGen ExAC gnomAD
CA6274922 rs782766959	404	K>N		No	ClinGen ExAC TOPMed gnomAD
rs186732605 CA6274921	407	C>Y		No	ClinGen 1000Genomes ExAC gnomAD
CA6274919 rs782480133	408	L>P		No	ClinGen ExAC gnomAD
rs369642482 CA6274917	412	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA6274915 rs781936090	413	D>G		No	ClinGen ExAC
COSM4145304 rs150357037 COSM4145303 CA6274916	413	D>Y	thyroid [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs1053913268 CA228565400	414	H>Y		No	ClinGen Ensembl
rs781947206 CA6274912	415	L>M		No	ClinGen ExAC gnomAD
CA382621454 rs1353121486	415	L>P		No	ClinGen TOPMed gnomAD
rs1441037655 CA382621442	417	G>C		No	ClinGen TOPMed gnomAD
CA382621435 rs1555161967	418	I>N		No	ClinGen gnomAD
rs782389662 CA6274909	423	L>P		No	ClinGen ExAC gnomAD
CA6274902 rs200079165	428	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6274903 rs141251272	428	P>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1204118195 CA382621275	429	E>D		No	ClinGen TOPMed gnomAD
rs1555161957 CA382621268	430	S>G		No	ClinGen gnomAD
CA382621231 rs1555161954	432	K>E		No	ClinGen gnomAD
CA6274898 rs782709619	432	K>R		No	ClinGen ExAC gnomAD
rs782742585 CA6274895	436	L>*		No	ClinGen ExAC TOPMed gnomAD
rs782742585 CA6274896	436	L>S		No	ClinGen ExAC TOPMed gnomAD
rs1555161950 CA382621112	439	F>S		No	ClinGen gnomAD
CA382621094 rs1450712125	440	V>F		No	ClinGen TOPMed
rs368744512 CA228565235	441	L>P		No	ClinGen ESP
CA6274894 rs782126011	441	L>V		No	ClinGen ExAC gnomAD
CA6274893 rs781982805	442	Q>*		No	ClinGen ExAC TOPMed gnomAD
CA228565229 rs782382714	442	Q>H		No	ClinGen Ensembl
TCGA novel	442	Q>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1566366674 CA382621036	444	N>D		No	ClinGen Ensembl
CA382621031 rs1566366657	444	N>S		No	ClinGen Ensembl
CA382621023 rs1555161947	445	G>R		No	ClinGen gnomAD
CA382620993 rs1555161946	447	D>N		No	ClinGen gnomAD
rs1409704205 CA382620950	449	M>I		No	ClinGen TOPMed gnomAD
rs781937716 CA6274890	450	I>T		No	ClinGen ExAC gnomAD
CA228565210 rs908957361	451	R>C		No	ClinGen TOPMed gnomAD
CA228565212 rs908957361	451	R>G		No	ClinGen TOPMed gnomAD
CA6274889 rs148283666	451	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs782076804 CA6274888	452	V>G		No	ClinGen ExAC TOPMed gnomAD
CA382620921 rs1365199954	452	V>L		No	ClinGen TOPMed
CA382620896 rs1555161938	453	K>E		No	ClinGen gnomAD
CA6274887 rs372105197	455	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs950560304 CA228565195	456	N>S		No	ClinGen gnomAD
rs782289410 CA382620795	459	P>A		No	ClinGen ExAC TOPMed gnomAD
rs782289410 CA6274885	459	P>S		No	ClinGen ExAC TOPMed gnomAD
rs782690822 CA6274884	461	C>F		No	ClinGen ExAC TOPMed gnomAD
rs782690822 CA382620738	461	C>S		No	ClinGen ExAC TOPMed gnomAD
rs574668776 CA6274882	462	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA6274883 rs574668776	462	T>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6274880 rs200674796	464	D>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1262599029 CA382620654	466	I>V		No	ClinGen TOPMed gnomAD
rs782642094 CA6274878	467	I>F		No	ClinGen ExAC gnomAD
rs182775518 CA228565121	467	I>T		No	ClinGen 1000Genomes gnomAD
CA6274876 rs781906446	471	I>M		No	ClinGen ExAC gnomAD
rs1555161935 CA382620576	471	I>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs782697834 CA6274875	472	T>S		No	ClinGen ExAC TOPMed gnomAD
CA382620549 rs1555161934	474	A>S		No	ClinGen gnomAD
TCGA novel	474	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
VAR_060322 CA228565085 rs3168263	475	T>P		No	ClinGen UniProt Ensembl dbSNP
rs1555161932 CA382620534	475	T>S		No	ClinGen gnomAD
rs781820404 CA6274873	478	I>T		No	ClinGen ExAC gnomAD
CA382620500 rs1475359404	478	I>V		No	ClinGen TOPMed
CA382620483 rs1566366392	479	H>R		No	ClinGen Ensembl
CA6274872 rs370615697	481	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA382620433 rs1555161928	482	Q>H		No	ClinGen gnomAD
rs1555161929 CA382620437	482	Q>L		No	ClinGen gnomAD
CA6274871 rs782104706	484	F>C		No	ClinGen ExAC
CA382620397 rs1555161926	485	V>L		No	ClinGen gnomAD
CA6274869 rs781994554	486	F>S		No	ClinGen ExAC gnomAD
rs552500014 CA6274868	487	V>M		No	ClinGen 1000Genomes ExAC gnomAD
rs377148351 CA6274867	488	S>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs77080347 CA6274866	489	M>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6274863 rs201937600	494	L>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs377348351 CA6274862	495	A>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs377348351 CA382620181	495	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs1315573236 CA382620186	495	A>S		No	ClinGen TOPMed gnomAD
CA6274861 rs782273811	496	M>V		No	ClinGen ExAC TOPMed gnomAD
CA6274860 rs782690321	497	L>P		No	ClinGen ExAC
rs1555161919 CA382620150	497	L>V		No	ClinGen gnomAD
rs781803989 CA6274858	502	S>A		No	ClinGen ExAC gnomAD
rs1555161916 CA382619991	502	S>C		No	ClinGen gnomAD
CA6274859 rs781803989	502	S>P		No	ClinGen ExAC gnomAD
CA6274855 rs782599418	504	W>R		No	ClinGen ExAC gnomAD
rs1555161912 CA382619912	506	M>V		No	ClinGen gnomAD
rs782179550 CA228564921	508	W>*		No	ClinGen Ensembl
CA382619847 rs1343338879	509	T>A		No	ClinGen TOPMed
rs782481215 CA6274854	509	T>M		No	ClinGen ExAC TOPMed gnomAD
rs374516075 CA6274852	513	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs191172184 CA6274851	513	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA382619743 rs1555161906	514	F>S		No	ClinGen gnomAD
CA382619724 rs1446998773	515	L>P		No	ClinGen TOPMed
CA382619726 rs1446998773	515	L>R		No	ClinGen TOPMed
TCGA novel	517	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	519	V>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1000043705 CA228564894	519	V>F		No	ClinGen Ensembl
rs369766483 CA6274849	523	I>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1025537590 CA228564893	523	I>T		No	ClinGen TOPMed gnomAD
rs377686600 CA6274848	524	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA382619562 rs1555161893	525	P>L		No	ClinGen gnomAD
CA6274847 rs781975900	528	S>R		No	ClinGen ExAC gnomAD
CA6274846 rs782764710	529	H>R		No	ClinGen ExAC gnomAD
rs1406606068 CA382619448	530	S>F		No	ClinGen TOPMed
rs532801312 CA6274845	532	Y>C		No	ClinGen 1000Genomes ExAC gnomAD
rs782019053 CA6274844	533	P>L		No	ClinGen ExAC TOPMed
CA6274842 rs782175628	535	C>Y		No	ClinGen ExAC TOPMed gnomAD
rs782339276 CA6274840	536	Y>*		No	ClinGen ExAC gnomAD
rs1592488204 CA382619274	539	D>N		No	ClinGen Ensembl
rs782226506 CA6274839	539	D>V		No	ClinGen ExAC gnomAD
CA382619172 rs1555161879	543	W>L		No	ClinGen gnomAD
rs1055336868 CA382619146	544	I>R		No	ClinGen gnomAD
rs1055336868 CA228564790	544	I>T		No	ClinGen gnomAD
rs941685272 CA228564781	545	D>H		No	ClinGen Ensembl
CA228564778 rs887467137	546	Q>L		No	ClinGen TOPMed gnomAD
CA382619095 rs1566366017	547	K>Q		No	ClinGen Ensembl
rs782267329 CA6274835	549	G>E		No	ClinGen ExAC gnomAD
CA6274833 rs782585990	550	F>C		No	ClinGen ExAC gnomAD
rs782454968 CA6274832	551	D>V		No	ClinGen ExAC gnomAD
CA6274831 rs781828241	552	E>A		No	ClinGen ExAC gnomAD
CA6274830 rs782743535	554	E>D		No	ClinGen ExAC gnomAD
CA382618922 rs1555161868	554	E>Q		No	ClinGen gnomAD
CA6274829 rs782508735	555	F>C		No	ClinGen ExAC gnomAD
rs781874017 COSM3981280 CA6274828 COSM3981281	555	F>L	ovary [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA382618855 rs868954014	557	T>A		No	ClinGen TOPMed gnomAD
CA6274827 rs782797106	557	T>I		No	ClinGen ExAC gnomAD
CA6274825 rs373615647	560	R>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA6274824 rs782726472	560	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs781967099 CA6274822	562	V>G		No	ClinGen ExAC gnomAD
rs1555161859 CA382618768	564	Q>*		No	ClinGen gnomAD
rs1555161859 CA382618770	564	Q>E		No	ClinGen gnomAD
CA382618751 rs1247372678	565	D>G		No	ClinGen TOPMed gnomAD
CA6274820 rs782255885	565	D>N		No	ClinGen ExAC gnomAD
CA382618741 rs1294534177	566	T>A		No	ClinGen TOPMed
CA6274819 rs782009981	566	T>I		No	ClinGen ExAC gnomAD
rs376050297 CA6274817	567	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs369394719 CA6274818	567	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA382618722 rs1555161854	568	I>L		No	ClinGen gnomAD
CA382618721 rs1555161854	568	I>V		No	ClinGen gnomAD
rs782598258 CA6274816	570	I>V		No	ClinGen ExAC gnomAD
rs1555161852 CA382618690	571	Q>R		No	ClinGen gnomAD
CA6274815 rs751078787	573	L>F		No	ClinGen ExAC TOPMed gnomAD
CA6274814 rs782244353	575	R>C		No	ClinGen ExAC TOPMed gnomAD
rs782651951 CA6274813	575	R>H		No	ClinGen ExAC TOPMed gnomAD
CA6274812 rs782539243	580	K>E		No	ClinGen ExAC gnomAD
CA382618616 rs1555161844	582	Q>*		No	ClinGen gnomAD
rs1555161844 CA382618617	582	Q>E		No	ClinGen gnomAD
CA228564617 rs976281671	582	Q>P		No	ClinGen TOPMed
COSM923042 CA6274811 COSM923041 rs371622116	583	Q>H	endometrium [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs368968622 CA6274810	584	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1423906955 CA382618578	587	C>W		No	ClinGen TOPMed
rs544142953 CA6274807	588	Y>C		No	ClinGen 1000Genomes ExAC gnomAD
rs782446187 CA6274808	588	Y>D		No	ClinGen ExAC gnomAD
rs943256741 CA228564564	589	R>G		No	ClinGen gnomAD
CA228564537 rs199809389	592	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA
CA382618534 rs782108944	593	Q>*		No	ClinGen ExAC gnomAD
CA6274805 rs782108944	593	Q>E		No	ClinGen ExAC gnomAD
CA6274804 rs200882357	594	T>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6274801 rs199933042	596	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA6274802 COSM1506552 rs200631446 COSM1506551	596	D>H	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD
CA382618445 rs1327040993	599	L>F		No	ClinGen TOPMed
CA382618427 rs1555161835	600	T>I		No	ClinGen gnomAD
CA382618419 rs1335276634	601	Q>R		No	ClinGen TOPMed gnomAD
CA6274799 rs374367178	605	A>T		No	ClinGen ESP ExAC gnomAD
CA382618363 rs1555161832	605	A>V		No	ClinGen gnomAD
CA6274798 rs781990522	606	S>P		No	ClinGen ExAC gnomAD
CA6274796 rs782276335	607	M>I		No	ClinGen ExAC gnomAD
rs1555161828 CA382618345	607	M>T		No	ClinGen gnomAD
rs142227201 CA6274797	607	M>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA382618322 rs368275758	608	Q>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs371108602 CA6274793	609	S>F		No	ClinGen ExAC TOPMed gnomAD
rs374832818 CA6274794	609	S>P		No	ClinGen ESP ExAC gnomAD
rs1555161824 CA382618282	611	F>L		No	ClinGen gnomAD
CA382618266 rs1555161823	613	K>Q		No	ClinGen gnomAD
CA382618234 rs1245878693	615	I>V		No	ClinGen TOPMed gnomAD
CA6274789 rs782653280	618	H>L		No	ClinGen ExAC gnomAD
rs782278614 CA6274790	618	H>Y		No	ClinGen ExAC gnomAD
rs377405344 CA382618178	619	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1271804693 CA382618165	620	Y>H		No	ClinGen TOPMed
CA6274786 rs764174737	621	V>A		No	ClinGen ExAC gnomAD
rs1555161812 CA382618129	622	I>M		No	ClinGen gnomAD
CA6274785 rs553154939	622	I>T		No	ClinGen 1000Genomes ExAC gnomAD
CA6274783 rs782760088	624	R>L		No	ClinGen ExAC TOPMed gnomAD
rs782760088 CA228564388	624	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6274784 rs781847840	624	R>W		No	ClinGen ExAC TOPMed gnomAD

No associated diseases with Q9BRP7

2 regional properties for Q9BRP7

Type	Name	Position	InterPro Accession
domain	Zinc finger, TRAF-type	12 - 103	IPR001293
domain	F-box domain	570 - 684	IPR001810

Functions

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

1 GO annotations of cellular component

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name	Definition
rRNA (uridine-N3-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.

1 GO annotations of biological process

Name	Definition
rRNA base methylation	The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.

2 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P08312	pheS	Phenylalanine--tRNA ligase alpha subunit	Escherichia coli (strain K12)	PR
Q9Y285	FARSA	Phenylalanine--tRNA ligase alpha subunit	Homo sapiens (Human)	PR

10	20	30	40	50	60
MAPRRLLLVG	EGNFSFAAAL	SETLDQSTQL	TATCLQRPAE	LARDPLAWEN	LQCLRERGID
70	80	90	100	110	120
VRFGVDCTQL	ADVFELHERE	FDQIYFIFPH	CGRKAGVAKN	RELLAKFFQS	CADVLAEEGE
130	140	150	160	170	180
VHVALCRGQG	GTPADKPQRE	WHNSWQVVAM	AALGGLILSD	VYPFSCKAVA	GYKCTGYRSQ
190	200	210	220	230	240
DKSFHVEGAL	NHIFTRSLPF	EGSQPRIFRI	KLGNQWFSFP	EPEALVGKLN	RGFLEAPSCH
250	260	270	280	290	300
PIKTINEKLI	AELGKVFPLK	RLKCSYPLLP	QEGTSVLPFW	NCDFLSAAFW	ISLHEDNSNS
310	320	330	340	350	360
ESLTGGTSQD	VEDFLVSFSE	LSLLKNPGRD	GKEEACEGTC	GQAKICLRPS	LLVHVQDVIE
370	380	390	400	410	420
VPDFLSGSLH	ILSGPVFQKC	HILPFTMPAF	HETLFILGVN	QNLKDGCLQS	LLDHLKGILD
430	440	450	460	470	480
SLLTQTLPES	SKLSSLVKFV	LQSNGKDYMI	RVKTHNFSPD	CTEDLIIGSV	ITSATSVIHK
490	500	510	520	530	540
DQCFVFVSMN	LDLLAMLVWC	ISDWRMLWTF	DNRFLKNFVP	GKIEPFKSHS	LYPPCYVHDV
550	560	570	580	590	600
SFWIDQKKGF	DELEFHTVAR	AVSQDTIISI	QFLSRFQHPK	TQQVSLCYRL	TYQTCDKALT
610	620
QQQVASMQSQ	FRKEIQQHLY	VIPR