Q9A4D6

PR
Gene name
carB
Protein name
Carbamoyl-phosphate synthase large chain
Names
Carbamoyl-phosphate synthetase ammonia chain
Species
Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus)
KEGG Pathway
ccr:CC_2900
EC number
6.3.4.16: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

462-538 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9A4D6

Entry ID Method Resolution Chain Position Source
AF-Q9A4D6-F1 Predicted AlphaFoldDB

No variants for Q9A4D6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9A4D6

No associated diseases with Q9A4D6

3 regional properties for Q9A4D6

Type Name Position InterPro Accession
domain CASTOR, ACT domain 72 - 140 IPR027795-1
domain CASTOR, ACT domain 262 - 322 IPR027795-2
domain CASTOR1, N-terminal 9 - 69 IPR040778

Functions

Description
EC Number 6.3.4.16 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
'de novo' UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKRTDISSI LIIGAGPIVI GQACEFDYSG VQACKALRAE GYRIILVNSN PATIMTDPDV
70 80 90 100 110 120
ADATYIEPIT PEMVAKIIEK ERPDALLPTM GGQTALNTAL ALEADGTLAK FGVEMIGAKA
130 140 150 160 170 180
EVIDKAEDRQ KFRDAMDKLG LESPRSRACH TLDEAMEGLE FVGLPAIIRP SFTLAGTGGG
190 200 210 220 230 240
IAYNVEEFKE IVERGLDLSP TTEVLVEESV LGWKEYEMEV VRDKADNCII VCSIENIDPM
250 260 270 280 290 300
GVHTGDSITV APALTLTDKE YQWMRAASIA VLREIGVETG GSNVQFAVNP ADGRMVVIEM
310 320 330 340 350 360
NPRVSRSSAL ASKATGFPIA KVAARLAVGY TLDELKNDIT GGATPASFEP SIDYVVTKIP
370 380 390 400 410 420
RFAFEKYPGS EPLLTTAMKS VGEVMAIGRT FKESVQKALR GLETGLSGFD EVEIAGADDP
430 440 450 460 470 480
DNGKEAVIRA LGVPTPDRLR VIAQAFRHGL TVDEVNAACS YEPWFLRQIA EIVRQEGWVK
490 500 510 520 530 540
AGGLPQTAQG FRELKAQGFS DARLAKLTAS TEKAVRAARQ ALNVRPVFKR IDSCAGEFLA
550 560 570 580 590 600
STPYMYSTYE FGALGQIPQC ESDPSAAKKA VILGGGPNRI GQGIEFDYCC CHAAFALDQI
610 620 630 640 650 660
GVESIMVNCN PETVSTDYDT SDRLYFEPLT AEDVLELLHV EMSKGTLAGV IVQFGGQTPL
670 680 690 700 710 720
KLAHALEEAG VPILGTSPDA IDLAEDRERF QQLLNGLNIA QPENAIARSW DEARAEGDKI
730 740 750 760 770 780
GFPFVMRPSY VLGGRGMEII RDHEAMERYI AGAGEISLEH PILLDHYLSR ATEVDVDALC
790 800 810 820 830 840
DGKDVFVAGV LEHIEEAGVH SGDSACSMPP FSLKAETVEE LKRQTVQMAL ALNVRGLMNV
850 860 870 880 890 900
QFAIEEPHSD NPRIYVLEVN PRASRTVPFV AKTIGQPVAA IAAKIMAGES LASFGLKDVP
910 920 930 940 950 960
YDHIAVKEAV FPFARFAGVD TVLGPEMRST GEVMGLDWKR DGETGMGPAF ARAFAKSQLG
970 980 990 1000 1010 1020
GGVKLPTKGT AFVSVKESDK PWIVEPVKLL QAAGFKVLST EGTQAYLAAQ GVQVEHVKKV
1030 1040 1050 1060 1070 1080
LEGRPHIVDV MKNGGVQLVF NTTEGKQALE DSFEIRRTAL MMKVPYYTTS AGALAAAQAI
1090
AGAPAEALDV RPLQSYAAE