Q9A0T3
Gene name |
ugl (SPy_0632, M5005_Spy0522) |
Protein name |
Unsaturated chondroitin disaccharide hydrolase |
Names |
Unsaturated glucuronyl hydrolase, SpyUGL |
Species |
Streptococcus pyogenes serotype M1 |
KEGG Pathway |
spz:M5005_Spy0522 |
EC number |
3.2.1.180: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9A0T3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9A0T3-F1 | Predicted | AlphaFoldDB |
No variants for Q9A0T3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9A0T3 | |||||
No associated diseases with Q9A0T3
No regional properties for Q9A0T3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9A0T3 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.180 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| chondroitin hydrolase activity | Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as |
| unsaturated chondroitin disaccharide hydrolase activity | Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| polysaccharide catabolic process | The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARPLKTIAL | EPIKQPERFT | KEDFLSQEDI | TQALDLALKQ | VRLNMDYFKE | DFPTPATKDN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QYAIMDNTEW | TNAFWTGCLW | LAYEYSGDDA | IKALAQANDL | SFLDRVTRDI | ELDHHDLGFL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YTPSCMAEWK | LLKTPESREA | ALKAADKLVQ | RYQDKGGFIQ | AWGELGKKED | YRLIIDCLLN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IQLLFFASQE | TGDNRYRDMA | INHFYASANH | VIRDDASAYH | TFYFDPETGD | PVKGVTRQGY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SDDSAWARGQ | AWGIYGIPLT | YRFLKEPELI | QLFKGMTHYF | LNRLPKDQVS | YWDLIFGDGS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EQSRDSSATA | IAVCGIHEML | KTLPDHDPDK | KTYEAAMHSM | LRALIKDYAN | KDLKPGAPLL |
| 370 | 380 | 390 | |||
| LHGVYSWHSG | KGVDEGNIWG | DYYYLEALLR | FYKDWNPYW |