AiPD: Autoinhibited Protein Database

Gene name	Srrt (Ars2, Asr2)
Protein name	Serrate RNA effector molecule homolog
Names	Arsenite-resistance protein 2
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:83701
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

27-114 (Predicted disordered autoinhibitory region) PR

27-114 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q99MR6-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388770113	24	D>E	No	EVA
rs3388806907	34	R>*	No	EVA
rs3388806880	66	F>S	No	EVA
rs3396325593	92	Y>*	No	EVA
rs3396251165	100	Y>*	No	EVA
rs3396192359	101	A>G	No	EVA
rs3388806872	114	P>A	No	EVA
rs3388792291	123	M>T	No	EVA
rs3388802766	129	P>L	No	EVA
rs3388784805	132	A>D	No	EVA
rs3388797756	158	S>F	No	EVA
rs3388794831	172	Y>F	No	EVA
rs3388792258	188	F>V	No	EVA
rs1134653313	233	F>V	No	EVA
rs13461404	279	K>N	No	EVA
rs261872540	284	S>N	No	EVA
rs3388781959	320	S>Y	No	EVA
rs32276635	341	A>V	No	EVA
rs3388792287	425	R>H	No	EVA
rs3396233804	450	A>E	No	EVA
rs3388803512	505	N>S	No	EVA
rs3388782002	505	N>Y	No	EVA
rs3388781977	530	L>R	No	EVA
rs3396316163	538	A>S	No	EVA
rs3388794093	590	E>D	No	EVA
rs3388794125	624	Y>*	No	EVA
rs3388806901	624	Y>F	No	EVA
rs3388803537	647	P>L	No	EVA
rs3388794062	651	N>I	No	EVA
rs3388784874	688	G>A	No	EVA
rs3388800330	776	L>F	No	EVA
rs3388797815	829	G>V	No	EVA
rs3388798864	830	A>G	No	EVA
rs3388802448	852	M>L	No	EVA
rs3388800404	859	A>D	No	EVA
rs3388784849	865	D>V	No	EVA
rs3396327439	866	L>M	No	EVA
rs3412992677	868	A>G	No	EVA
rs3388797807	868	A>S	No	EVA
rs3396325617	869	P>S	No	EVA
rs3396233729	870	D>E	No	EVA
rs3396233819	870	D>N	No	EVA
rs3396192351	871	D>E	No	EVA
rs3396233773	873	D>N	No	EVA
rs3396192213	874	F>I	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q99MR6

		Description
EC Number
Subcellular Localization	Nucleus, nucleoplasm Cytoplasm	Predominantly nuclear Shuttles between the nucleus and the cytoplasm in a CRM1-dependent way
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nuclear body	Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
protein-containing complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
ribonucleoprotein complex	A macromolecular complex that contains both RNA and protein molecules.

Name	Definition
DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
mRNA cap binding complex binding	Binding to a mRNA cap binding complex.
protein-macromolecule adaptor activity	The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.

Name	Definition
mRNA processing	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
neuronal stem cell population maintenance	Any process in by an organism or tissue maintains a population of neuronal stem cells.
positive regulation of neurogenesis	Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
primary miRNA processing	A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.
regulation of DNA-templated transcription	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9BXP5	SRRT	Serrate RNA effector molecule homolog	Homo sapiens (Human)	PR