Q99J36
Gene name |
Thumpd1 |
Protein name |
THUMP domain-containing protein 1 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:233802 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q99J36
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q99J36-F1 | Predicted | AlphaFoldDB |
21 variants for Q99J36
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs259998795 | 13 | A>G | No | EVA | |
| rs3388921379 | 119 | S>* | No | EVA | |
| rs3388945156 | 122 | S>I | No | EVA | |
| rs3398495716 | 143 | H>N | No | EVA | |
| rs3398702707 | 147 | D>V | No | EVA | |
| rs3398426050 | 148 | M>L | No | EVA | |
| rs3398490805 | 149 | Y>N | No | EVA | |
| rs232835043 | 159 | I>F | No | EVA | |
| rs3388945845 | 207 | H>R | No | EVA | |
| rs3388945867 | 217 | L>V | No | EVA | |
| rs3388925448 | 262 | Y>F | No | EVA | |
| rs3388936298 | 276 | P>S | No | EVA | |
| rs3388941284 | 279 | K>R | No | EVA | |
| rs3388921439 | 287 | K>I | No | EVA | |
| rs49593623 | 295 | S>N | No | EVA | |
| rs50089272 | 299 | P>A | No | EVA | |
| rs3388939241 | 321 | E>D | No | EVA | |
| rs213588766 | 329 | D>G | No | EVA | |
| rs249506698 | 331 | K>E | No | EVA | |
| rs3388899067 | 337 | Q>R | No | EVA | |
| rs235679563 | 347 | N>K | No | EVA |
No associated diseases with Q99J36
1 regional properties for Q99J36
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Thrombospondin type-1 (TSP1) repeat | 339 - 392 | IPR000884 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATTAQQSPQ | PVAGKRKGKS | QFLPAKRARR | GDAGGPRQLE | PGLQGILITC | NMNERKCVEE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AYSLLNEYGD | DMYGPEKFID | KDQQPSGSEG | EDDDAEAALK | KEVGDIKAST | EKRLRRFQSV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESGANNVVFI | RTLGIEPEKL | VHHILQDMYK | TKKKKTRVIL | RMLPISGTCK | AFLEDMKKYA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ETFLEPWFKA | PNKGTFQIVY | KSRNNSHMNR | EEVIKELAGI | VGSLNSENKV | DLTNPEYTVV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEIIKAVCCL | SVVKDYVLFR | KYNLQEVVKS | AKDSQPHPKL | GNGKEAKLEP | DSKLSQSDPP |
| 310 | 320 | 330 | 340 | ||
| EGNQVAPESI | EELGQTEPGS | ETQAGSEGDA | KPEPESQVSE | VPKTNENELS |