Q99369

PR
Gene name
FSH3 (YOR280C)
Protein name
Family of serine hydrolases 3
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YOR280C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

201-266 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q99369

Entry ID Method Resolution Chain Position Source
AF-Q99369-F1 Predicted AlphaFoldDB

5 variants for Q99369

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-845686 36 Y>H No SGRP
s15-845659 45 H>Y No SGRP
s15-845499 98 N>S No SGRP
s15-845382 137 T>I No SGRP
s15-845259 178 E>G No SGRP

No associated diseases with Q99369

4 regional properties for Q99369

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 222 - 399 IPR002314
domain Aminoacyl-tRNA synthetase, class II 171 - 409 IPR006195
domain Serine-tRNA synthetase, type1, N-terminal 1 - 107 IPR015866
domain Serine-tRNA ligase catalytic core domain 119 - 416 IPR033729

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
carboxylic ester hydrolase activity Catalysis of the hydrolysis of a carboxylic ester bond.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEKKKVLML HGFVQSDKIF SAKTGGLRKN LKKLGYDLYY PCAPHSIDKK ALFQSESEKG
70 80 90 100 110 120
RDAAKEFNTS ATSDEVYGWF FRNPESFNSF QIDQKVFNYL RNYVLENGPF DGVIGFSQGA
130 140 150 160 170 180
GLGGYLVTDF NRILNLTDEQ QPALKFFISF SGFKLEDQSY QKEYHRIIQV PSLHVRGELD
190 200 210 220 230 240
EVVAESRIMA LYESWPDNKR TLLVHPGAHF VPNSKPFVSQ VCNWIQGITS KEGQEHNAQP
250 260
EVDRKQFDKP QLEDDLLDMI DSLGKL