Q99297
Gene name |
ODC2 (YOR222W, YOR50-12) |
Protein name |
Mitochondrial 2-oxodicarboxylate carrier 2 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YOR222W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q99297
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q99297-F1 | Predicted | AlphaFoldDB |
2 variants for Q99297
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s15-758883 | 185 | L>F | No | SGRP | |
| s15-758898 | 190 | Y>D | No | SGRP |
No associated diseases with Q99297
3 regional properties for Q99297
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Mitochondrial substrate/solute carrier | 9 - 109 | IPR018108-1 |
| repeat | Mitochondrial substrate/solute carrier | 116 - 200 | IPR018108-2 |
| repeat | Mitochondrial substrate/solute carrier | 209 - 301 | IPR018108-3 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP:ADP antiporter activity | Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out). |
| dicarboxylic acid transmembrane transporter activity | Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups. |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial ADP transmembrane transport | The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion. |
| mitochondrial ATP transmembrane transport | The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion. |
| mitochondrial transport | Transport of substances into, out of or within a mitochondrion. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSDSNAKPL | PFIYQFISGA | VAGISELTVM | YPLDVVKTRF | QLEVTTPTAA | AVGKQVERYN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GVIDCLKKIV | KKEGFSRLYR | GISSPMLMEA | PKRATKFACN | DQYQKIFKNL | FNTNETTQKI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SIAAGASAGM | TEAAVIVPFE | LIKIRMQDVK | SSYLGPMDCL | KKTIKNEGIM | GLYKGIESTM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WRNALWNGGY | FGVIYQVRNS | MPVAKTKGQK | TRNDLIAGAI | GGTVGTMLNT | PFDVVKSRIQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SVDAVSSAVK | KYNWCLPSLL | VIYREEGFRA | LYKGFVPKVC | RLAPGGSLML | VVFTGMMNFF |
| RDLKYGH |