Q99189
Gene name |
MTR10 (YOR160W) |
Protein name |
mRNA transport regulator MTR10 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YOR160W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q99189
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q99189-F1 | Predicted | AlphaFoldDB |
20 variants for Q99189
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s15-633845 | 2 | D>E | No | SGRP | |
| s15-634308 | 157 | S>P | No | SGRP | |
| s15-634429 | 197 | S>N | No | SGRP | |
| s15-634571 | 244 | E>D | No | SGRP | |
| s15-634960 | 374 | S>C | No | SGRP | |
| s15-634983 | 382 | N>D | No | SGRP | |
| s15-635170 | 444 | S>N | No | SGRP | |
| s15-635178 | 447 | I>L | No | SGRP | |
| s15-635239 | 467 | N>S | No | SGRP | |
| s15-635242 | 468 | T>I | No | SGRP | |
| s15-635322 | 495 | G>S | No | SGRP | |
| s15-635683 | 615 | K>R | No | SGRP | |
| s15-635835 | 666 | T>A | No | SGRP | |
| s15-635838 | 667 | L>M | No | SGRP | |
| s15-635863 | 675 | T>I | No | SGRP | |
| s15-636268 | 810 | A>V | No | SGRP | |
| s15-636298 | 820 | Y>S | No | SGRP | |
| s15-636423 | 862 | E>K | No | SGRP | |
| s15-636435 | 866 | A>T | No | SGRP | |
| s15-636571 | 911 | T>I | No | SGRP |
No associated diseases with Q99189
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nuclear periphery | The portion of the nuclear lumen proximal to the inner nuclear membrane. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| nuclear localization sequence binding | Binding to a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus. |
| small GTPase binding | Binding to a small monomeric GTPase. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| protein import into nucleus | The directed movement of a protein from the cytoplasm to the nucleus. |
| RNA import into nucleus | The import of RNA from the cytoplasm to the nucleus. |
| RNA localization | A process in which RNA is transported to, or maintained in, a specific location. |
| snRNA import into nucleus | The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus. |
| tRNA transport | The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDNLQVSDIE | TALQCISSTA | SQDDKNKALQ | FLEQFQRSTV | AWSICNEILS | KEDPTNALLE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LNIFAAQTLR | NKVTYDLSQL | ENNLPQFKDS | LLTLLLSHNQ | KLIITQLNVA | LARLAIQFLE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WQNPIFEIIS | LLNSSPSILL | NFLRILPEET | LDIASTSLTE | VEFNSRIHEL | IDPIAEDVLK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FLVSCIDLLQ | NTDGNSSSSI | SLEQILRCLN | SWSYEFPVEQ | LLTVQPLINL | VFETISNGNE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SDMEAFDSAI | DCLCVILRES | RDTTNEQLIS | ALFHQLMLLQ | EKLLPTLFTD | HPLNDEYDDD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLEGMTRLFV | EAGEAWSVVI | SKNPDFFKPM | VLVLLMLTCK | NEDLDVVSYT | FPFWFNFKQS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LVLPRYQESR | KAYSDIFVKL | INGIITHLQY | PSGQFSSKEE | EDKFKDFRYH | MGDVLKDCTA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VVGTSEALSQ | PLIRIKSAIE | NNNSWQIMEA | PLFSLRTMAK | EISLTENTIL | PEIIKIICNL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PEQAKIRYAS | TLVLGRYTEW | TAKHPELLEV | QLQYIFNGFQ | LHEGSSDMQS | IITASSHALM |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FFCSDCSKLL | VGYIDQLINF | FLNVQSSIDI | ESQFELCQGL | SAVINNQPEA | KVSVIFQKLV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DDNLRQIEAL | IPQWKANPTL | LAPQIADKID | LLYALFEELK | PRYNYPQQGS | EPLLPRIEFI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| WKALRTLLVD | AGAMTDSIIV | ERVAKLLRRI | FERFHVFCEP | ILPSVAEFLI | QGYLTTGFGS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| YLWCSGSLIV | IFGDDESFPI | SPSLKDAVWK | FALSQCETFI | LNFNKFDKLQ | LNDYHEAIID |
| 790 | 800 | 810 | 820 | 830 | 840 |
| FFSLISDLIM | FYPGAFLNST | ELLGPVLNVA | LECVNKLDNY | DAYICILRCL | DDIISWGFKT |
| 850 | 860 | 870 | 880 | 890 | 900 |
| PPISTVSIEI | VPDEWRKQVI | NEVVIAHGNQ | LILVLFIGLV | TTFENTAHSD | AISCIVKCLR |
| 910 | 920 | 930 | 940 | 950 | 960 |
| ILTEANNNDA | TICIDWIYKV | VEQLGQVTLN | ERDNLAKAVV | EGLNSKDYRK | VREGIRAFVG |
| 970 | |||||
| WYSRKNINSR | FE |