Q98PW8

PR
Gene name
pfkA
Protein name
ATP-dependent 6-phosphofructokinase
Names
ATP-PFK, Phosphofructokinase, Phosphohexokinase
Species
Mycoplasmopsis pulmonis (strain UAB CTIP) (Mycoplasma pulmonis)
KEGG Pathway
mpu:MYPU_6010
EC number
2.7.1.11: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

278-326 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q98PW8

Entry ID Method Resolution Chain Position Source
AF-Q98PW8-F1 Predicted AlphaFoldDB

No variants for Q98PW8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q98PW8

No associated diseases with Q98PW8

2 regional properties for Q98PW8

Type Name Position InterPro Accession
domain Phosphofructokinase domain 4 - 275 IPR000023
conserved_site Phosphofructokinase, conserved site 246 - 264 IPR015912

Functions

Description
EC Number 2.7.1.11 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
6-phosphofructokinase activity Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
fructose 6-phosphate metabolic process The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIKKIAILTS GGDSPGMNNA IRAIIKTARL YDIETYLVYE GFLGLYNGWI KPSEGIDEDS
70 80 90 100 110 120
YINKGGTFIF SARFVEFAQE KYRQVAKENL LKLGIEALVV IGGDGSYKGA QKLHEMGIKT
130 140 150 160 170 180
IALPGTIDND ITSSDFTIGY DTALNTIVEA VDKIRDTASS HKRCIMVEVM GHGASDLALY
190 200 210 220 230 240
SGMATGSEII VSNDYKLSVE EMAKIVKKQF EKPNKRSVII TVSEFVFKDL QQVAKQIEEL
250 260 270 280 290 300
TNITTKAVVL AHIQRGGYPS ARERINATIL GKHAVLRLKQ GQSGIALGLI KNQVAATPIL
310 320
EALAMPQTRK DLLERRTKSY NDINQA