Q97ZN1

PR
Gene name
argS
Protein name
Arginine--tRNA ligase
Names
Arginyl-tRNA synthetase, ArgRS
Species
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
KEGG Pathway
sso:SSO0857
EC number
6.1.1.19: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q97ZN1

Entry ID Method Resolution Chain Position Source
AF-Q97ZN1-F1 Predicted AlphaFoldDB

No variants for Q97ZN1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97ZN1

No associated diseases with Q97ZN1

3 regional properties for Q97ZN1

Type Name Position InterPro Accession
domain Arginyl tRNA synthetase N-terminal domain 1 - 82 IPR005148
domain DALR anticodon binding 509 - 625 IPR008909
domain Arginyl-tRNA synthetase, catalytic core domain 102 - 501 IPR035684

Functions

Description
EC Number 6.1.1.19 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
arginine-tRNA ligase activity Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
arginyl-tRNA aminoacylation The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIIGRAKKE LAEYVAAQLG ISEEEVFKNI TYPPREELGD LSLALPSLIK GNINEKAKLL
70 80 90 100 110 120
QEYKGELIER IEVAGIYLNA RLNLRNIFVS IFSKLDDSYG LEKIEKPKRI VVEHTSANPI
130 140 150 160 170 180
HPLHIGHLRN TILGDALARA LKARGHSVNV RFYVNDTGRQ VAVLIYGLKL LGFPDPEPNV
190 200 210 220 230 240
KKDLWLGIIY AMTNVILEIR KLREELKKLS ESEYREKVRE LDELIVIAND LRNRNEVLFD
250 260 270 280 290 300
KLADAINAKE EPEKEIGEII KKYEEGNDEL KGIIRKYISY ALEGFSETLS KLNIRFDNFD
310 320 330 340 350 360
YESDLLWENM VNEVLKALLS SSAKIPYKGV IALDLDSFLG DEARSKLRIP KGLKIPPLVL
370 380 390 400 410 420
MRSDGTTLYT VRDIAYTIFK FNQFNADFVI NVIAEEQYIP QIQLRGALEL LGYSRFAENL
430 440 450 460 470 480
LHYSYGMVNI QGLRMSGRLG KIITIDEIYE KLDNIVRNKL KEKGGNMENI DDIANAALRY
490 500 510 520 530 540
AILSVSANKP LSFDLNRITS FEQNSGPYLQ YTYARAANIL AKSTENLSMD KVDFSDLVGD
550 560 570 580 590 600
KRNILILIAK FPEVFKNAVD NLRLEDLVAF LRELSDIFNS WYDKERVLQE QDPRKRMLRL
610 620
YIVKGVSVVL KNGLSVLGIR SLERM