Q97WH0

PR
Gene name
rad50
Protein name
DNA double-strand break repair Rad50 ATPase
Names
Species
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
KEGG Pathway
sso:SSO2249
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

156-372 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q97WH0

Entry ID Method Resolution Chain Position Source
AF-Q97WH0-F1 Predicted AlphaFoldDB

No variants for Q97WH0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97WH0

No associated diseases with Q97WH0

2 regional properties for Q97WH0

Type Name Position InterPro Accession
domain RAD50, zinc hook 380 - 478 IPR013134
domain Rad50/SbcC-type AAA domain 5 - 226 IPR038729

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
double-strand break repair The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRIDKITLTN FLSHEHSEIQ FMGEINVIVG QNGAGKSSII DGIVFSLFRT HSRGNNDNLI
70 80 90 100 110 120
RKGSNRGSVT LYLSNEKDKI EIIRDIRSTT EDRLIRNQFP IARSATVVSN EIEKILGIDK
130 140 150 160 170 180
DIALSTIIVR QGELDKILEN FQEIMGKILK LELIEKLIDS RGPIVEFRKN LENKLRELDR
190 200 210 220 230 240
IEQDYNNFKK TVEEKRARVL ELKKDKEKLE DEIKNLEKRI KDIKDQFDEY EKKRNQYLKL
250 260 270 280 290 300
TTTLKIKEGE LNELNRSIEE LRKQTENMDQ LEKEINELEN LRNIKLKFEK YEVLAKSHTE
310 320 330 340 350 360
MSANVINLEK EIEEYEKAIR RKEELEPKYL KYKELERKLE ELQPKYQQYL KLKSDLDSKL
370 380 390 400 410 420
NLKERLEKDA SELSNDIDKV NSLEQKVEET RKKQLNLRAQ LAKVESLISE KNEIINNISQ
430 440 450 460 470 480
VEGETCPVCG RPLDEEHKQK IIKEAKSYIL QLELNKNELE EELKKITNEL NKIEREYRRL
490 500 510 520 530 540
SNNKASYDNV MRQLKKLNEE IENLHSEIES LKNIDEEIKK INEEVKELKL YYEEFMRLSK
550 560 570 580 590 600
YTKEELDKKR VKLDEMKKKK EEIEKEMRGL ESELKGLDRK ALESKILDLE NKRVKLDEMK
610 620 630 640 650 660
KKKGILEDYI RQVKLLQEEV KNLREEVNII QFDENRYNEL KTSLDAYNLS LKEKENRKSR
670 680 690 700 710 720
IEGELESLEK DIEEISNRIA NYELQLKDRE KIINAINKLE KIRSALGERK LQSYIIMTTK
730 740 750 760 770 780
QLIENNLNDI ISKFDLSIKN VEMEIMPKTG RGRSSSGDIL VYTNSGDTLP IVSLSGGERI
790 800 810 820 830 840
ALSIALRLAI AKALMSNTNF FILDEPTIHL DDQRKAYLIE IIRAAKESVP QIIVVTHDEE
850 860
VVQAADYVIR VEKRGNKSFV REET