Q97VS5

PR
Gene name
pckG
Protein name
Phosphoenolpyruvate carboxykinase [GTP]
Names
PEP carboxykinase, PEPCK
Species
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
KEGG Pathway
sso:SSO2537
EC number
4.1.1.32: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

25-96 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q97VS5

Entry ID Method Resolution Chain Position Source
AF-Q97VS5-F1 Predicted AlphaFoldDB

No variants for Q97VS5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97VS5

No associated diseases with Q97VS5

2 regional properties for Q97VS5

Type Name Position InterPro Accession
domain Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain 233 - 583 IPR035077
domain Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal 30 - 228 IPR035078

Functions

Description
EC Number 4.1.1.32 Carboxy-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
manganese ion binding Binding to a manganese ion (Mn).
phosphoenolpyruvate carboxykinase (GTP) activity Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.

6 GO annotations of biological process

Name Definition
cellular response to glucose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
glycerol biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate.
propionate catabolic process The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.
response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
response to starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKSSLDFLNN FIQRDAVKKL ESINNYPLIE FLNSVVKLCE PDSVYLITGS DEEKEYIRKK
70 80 90 100 110 120
ALESKEEIRL QTSGHTIHFD HPLDQARARE DTFILSDTKI PYVNTKPRNE GLSEMLTLLK
130 140 150 160 170 180
GSMRGREMYV GFYSLGPRNS PFQILAVQVT DSPYVIHSEN ILYRIAFEDF SNNTKFLRFV
190 200 210 220 230 240
HSKGEPDIKK RRIMIDLANN TVYSVNTTYA GNSVGLKKLA LRLTIMKAVE EGWLSEHMAI
250 260 270 280 290 300
VGFNGDKGIH YFTASFPSGS GKTSTSMIGN LISDDLAFIR EFEGLPKAVN PEIGVFGIIQ
310 320 330 340 350 360
GINARDDPII WEVLHKPGEV IFSNVLMTED GDVYWEGSEL PKPERGYNHE GRWDRESGKP
370 380 390 400 410 420
ASHPNARFTV PLTSFSNLDK NWDNPNGVII DGIIFGVRDY STLVPVVEAF SWSHGVITIG
430 440 450 460 470 480
ASMESARTSA VIGKSDELEF NPMAILDFMP ISLSRYLRNY LNFGKRLRKS PKIFGFNYFL
490 500 510 520 530 540
KDDNKFLNSK EDKKVWVSWA VKRVEETANA IYTPIGLIPF YEDLKALFKR VLGKEYGKEE
550 560 570 580 590 600
YEKQFTIKLR KYLEKTERII EIYLKFEDIP SEVINELKMQ KERIVDYINK YGDSVSPFRL
EKD