Q97S57

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
KEGG Pathway
spn:SP_0556
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-389 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q97S57

Entry ID Method Resolution Chain Position Source
AF-Q97S57-F1 Predicted AlphaFoldDB

No variants for Q97S57

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97S57

No associated diseases with Q97S57

6 regional properties for Q97S57

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 460 - 627 IPR000795
domain Small GTP-binding protein domain 462 - 619 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 380 - 431 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 735 - 850 IPR023115
domain Translation initiation factor IF-2, domain II 635 - 730 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKRLYEIA KELGKESKEV VARAKELGLD VKSHSSSVEE AVAAKIAASF KPAAAPKVEA
70 80 90 100 110 120
KPAAPKVSAE KKAEKSEPAK PAVAKEEAKP AAPKASAEKK AEKSEPVKPA VAKEEAKPAE
130 140 150 160 170 180
PVTPKTEKVA AKPQSRNFKA EREARAKEQA ERRKQNKGNN RDQQQNGNRQ KNDGRNGGKQ
190 200 210 220 230 240
GQSNRDNRRF NDQAKKQQGQ QKRRNERRQQ EDKRSNQAAP RIDFKARAAA LKAEQNAEYA
250 260 270 280 290 300
RSSEERFKQY QAAKEALAQA NKRKEPEEIF EEAAKLAEQA QQVQAVVEVV PEKKEPAVDT
310 320 330 340 350 360
RRKKQARPDK NRDDYDHEED GPRKQQKNRS SQNQVRNQKN SNWNNNKKNK KGNNKNNRNQ
370 380 390 400 410 420
TPKPVTERKF HELPTEFEYT DGMTVAEIAK RIKREPAEIV KKLFMMGVMA TQNQSLDGET
430 440 450 460 470 480
IELLMVDYGI EAKQKVEVDN ADIERFFVED GYLNEDELVE RPPVVTIMGH VDHGKTTLLD
490 500 510 520 530 540
TLRNSRVATG EAGGITQHIG AYQIVENGKK ITFLDTPGHA AFTSMRARGA SVTDITILVV
550 560 570 580 590 600
AADDGVMPQT IEAINHSKAA NVPIIVAINK IDKPGANPER VIGELAEHGV MSTAWGGDSE
610 620 630 640 650 660
FVEISAKFNQ NIEELLETVL LVAEIQELKA DPTVRAIGTV IEARLDKGKG AVATLLVQQG
670 680 690 700 710 720
TLNVQDPIVV GNTFGRVRAM TNDLGRRVKV AGPSTPVSIT GLNEAPMAGD HFAVYEDEKS
730 740 750 760 770 780
ARAAGEERAK RALMKQRQAT QRVSLENLFD TLKAGELKSV NVIIKADVQG SVEALSASLQ
790 800 810 820 830 840
KIDVEGVKVT IVHSAVGAIN ESDVTLAEAS NAFIVGFNVR PTPQARQQAE ADDVEIRLHS
850 860 870 880 890 900
IIYKVIEEME EAMKGMLDPE FEEKVIGEAV IRETFKVSKV GTIGGFMVIN GKVARDSKVR
910 920 930 940 950
VIRDGVVIYD GELASLKHYK DDVKEVTNGR EGGLMIDGYN DIKMDDVIEA YVMEEIKR