Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

7 structures for Q97R12

Entry ID Method Resolution Chain Position Source
5XJ1 X-ray 175 A A 1-454 PDB
5XJ2 X-ray 284 A A/B/C/D 1-454 PDB
5ZQ0 X-ray 200 A A 1-452 PDB
5ZQ1 X-ray 310 A A 1-452 PDB
5ZQ8 X-ray 218 A A/B 1-454 PDB
5ZTH X-ray 324 A A 1-452 PDB
AF-Q97R12-F1 Predicted AlphaFoldDB

No variants for Q97R12

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97R12

No associated diseases with Q97R12

3 regional properties for Q97R12

Type Name Position InterPro Accession
domain TRAM domain 1 - 59 IPR002792
active_site RNA methyltransferase TrmA, active site 381 - 412 IPR030390
conserved_site RNA methyltransferase TrmA, conserved site 433 - 443 IPR030391

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
RNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.

1 GO annotations of biological process

Name Definition
ncRNA processing Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKKNDIVEV EIVDLTHEGA GVAKVDGLVF FVENALPSEK ILMRVLKVNK KIGFGKVEKY
70 80 90 100 110 120
LVQSPHRNQD LDLAYLRSGI ADLGHLSYPE QLKFKTKQVK DSLYKIAGIA DVEVAETLGM
130 140 150 160 170 180
EHPVKYRNKA QVPVRRVNGV LETGFFRKNS HNLMPLEDFF IQDPVIDQVV VALRDLLRRF
190 200 210 220 230 240
DLKPYDEKEQ SGLIRNLVVR RGHYSGQIMV VLVTTRPKVF RVDQLIEQVI KQFPEIVSVM
250 260 270 280 290 300
QNINDQNTNA IFGKEWRTLY GQDYITDQML GNDFQIAGPA FYQVNTEMAE KLYQTAIDFA
310 320 330 340 350 360
ELKKDDVIID AYSGIGTIGL SVAKHVKEVY GVELIPEAVE NSQKNASLNK ITNAHYVCDT
370 380 390 400 410 420
AENAMKKWLK EGIQPTVILV DPPRKGLTES FIKASAQTGA DRIAYISCNV ATMARDIKLY
430 440 450 460 470 480
QELGYELKKV QPVDLFPQTH HVETVALLSK LDVDKHISVE IELDEMDLTS AESKATYAQI
490 500 510 520 530 540
KEYVWNKFEL KVSTLYIAQI KKKCGIELRE HYNKSKKDKQ IIPQCTPEKE EAIMDALRHF
KMI