Q97Q18
Gene name |
hprK |
Protein name |
HPr kinase/phosphorylase |
Names |
HPrK/P, HPr(Ser) kinase/phosphorylase |
Species |
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |
KEGG Pathway |
spn:SP_1413 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q97Q18
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q97Q18-F1 | Predicted | AlphaFoldDB |
No variants for Q97Q18
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q97Q18 | |||||
No associated diseases with Q97Q18
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| phosphorelay sensor kinase activity | Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
| protein serine/threonine/tyrosine kinase activity | Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| regulation of carbohydrate metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMSVLVKEVI | EKLRLDIVYG | EPELLEKEIN | TADITRPGLE | MTGYFDYYTP | ERIQLLGMKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WSYLISMPSN | SRYEVLKKMF | LPETPAVIVA | RGLVVPEEML | KAARECKIAI | LTSRAATSRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGELSSYLDS | RLAERTSVHG | VLMDIYGMGV | LIQGDSGIGK | SETGLELVKR | GHRLVADDRV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DIFAKDEITL | WGEPAEILKH | LIEIRGVGII | DVMSLYGASA | VKDSSQVQLA | VYLENYDTHK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TFDRLGNNAE | ELEVSGVAIP | RIRIPVKTGR | NISVVIEAAA | MNYRAKEMGF | DATRLFDERL |
| 310 | |||||
| TSLIARNEVQ | NA |