Q97M37

PR
Gene name
nfi
Protein name
Endonuclease V
Names
Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V
Species
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
KEGG Pathway
cac:CA_C0363
EC number
3.1.21.7: Endodeoxyribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-55 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q97M37

Entry ID Method Resolution Chain Position Source
AF-Q97M37-F1 Predicted AlphaFoldDB

No variants for Q97M37

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97M37

No associated diseases with Q97M37

2 regional properties for Q97M37

Type Name Position InterPro Accession
domain FeS cluster biogenesis 17 - 112 IPR000361
domain NIF system FeS cluster assembly, NifU, C-terminal 127 - 198 IPR001075

Functions

Description
EC Number 3.1.21.7 Endodeoxyribonucleases producing 5'-phosphomonoesters
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
deoxyribonuclease V activity Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTVNVHGFE ASSKEEFQVI QSSLVKRIKL ISDFKEEDIK LCAGVDLAYW TKGEKQYGVC
70 80 90 100 110 120
CIIVIDYNTG EIIEKAYDYG EIEVPYMPGF LAFRELPLVI KTVKKLKNEP DIFMFDGNGY
130 140 150 160 170 180
LHYNHMGIAT HASFFLNKPT IGVAKSYLKV AGVDFEMPES FEGAFKDIVI NEEVYGRVLR
190 200 210 220 230
TKKDVKPIFV SCGNYIDLET CTKICSKLIN NDSRLPITVR LADLETHKRR SELS