Q97GC0

PR
Gene name
fprA2 (CA_C2449)
Protein name
Flavo-diiron protein FprA2
Names
FDP 2, Flavoprotein A2, H(2)O-forming NADH oxidase, NADH oxidase, NADH:O(2) oxidoreductase
Species
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
KEGG Pathway
cac:CA_C2449
EC number
1.6.3.4: With oxygen as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

207-281 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q97GC0

Entry ID Method Resolution Chain Position Source
AF-Q97GC0-F1 Predicted AlphaFoldDB

No variants for Q97GC0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97GC0

No associated diseases with Q97GC0

3 regional properties for Q97GC0

Type Name Position InterPro Accession
conserved_site Flavodoxin, conserved site 259 - 275 IPR001226
domain Metallo-beta-lactamase 34 - 211 IPR001279
domain Flavodoxin/nitric oxide synthase 257 - 397 IPR008254

Functions

Description
EC Number 1.6.3.4 With oxygen as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

5 GO annotations of molecular function

Name Definition
electron transfer activity Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
iron ion binding Binding to an iron (Fe) ion.
nitric oxide reductase activity Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide.
oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule.

2 GO annotations of biological process

Name Definition
reactive oxygen species metabolic process The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPAIKIKDNI FSVGVLNPSL RIFDIIMKTE YGTSYNAYLI KGKKNVLIDT VHGRFFDEYL
70 80 90 100 110 120
ENIKSVIDPS SIDYVIMNHC EPDHSGSLAR LYEVAPQIKV IASNAGKIYL KNITNKETLD
130 140 150 160 170 180
VKAVKTNDTL DIGNGKVLKF AIAPFLHWPD SMFTILEEDK IAFTCDFLGC HFCEPRMFDT
190 200 210 220 230 240
KITYMPKYEK SFKEYYDAIF SPFKPYVVKG LDILDALDLD FIATSHGPIL TREGLLAASK
250 260 270 280 290 300
QKYRDLSSEI QSTTKYIPIF YCSAYGNTEI LANEIASGIK SVLNDANIEM LDIINYDYSD
310 320 330 340 350 360
LKEKINICDA FMLGTPTINK DALFPIWELI GGIDAVNCKN KPASAFGSFG WSGEAIPFVI
370 380 390
SRLKELKLKV FQDGFTCLFV PSEDDIKKAF KFGEDFAKSI