Q97EB8

PR
Gene name
glyQS
Protein name
Glycine--tRNA ligase
Names
Glycyl-tRNA synthetase, GlyRS
Species
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
KEGG Pathway
cac:CA_C3195
EC number
6.1.1.14: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

344-462 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q97EB8

Entry ID Method Resolution Chain Position Source
AF-Q97EB8-F1 Predicted AlphaFoldDB

No variants for Q97EB8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q97EB8

No associated diseases with Q97EB8

4 regional properties for Q97EB8

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 164 - 340 IPR002314
domain Anticodon-binding 372 - 460 IPR004154
domain Aminoacyl-tRNA synthetase, class II 136 - 377 IPR006195
domain Glycyl-tRNA synthetase-like core domain 10 - 344 IPR033731

Functions

Description
EC Number 6.1.1.14 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glycine-tRNA ligase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

1 GO annotations of biological process

Name Definition
glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKDEKTMDKI VSLAKNRGFV FAGSEIYGGL ANSWDYGPLG VELKNNVKKL WWKKFVQDNT
70 80 90 100 110 120
YNVGLDCAIL MNSEVWVASG HLGGFSDPLM DCKECKSRFR ADKIVEDYLT EQGAEVASAD
130 140 150 160 170 180
GWSNEKLENF IKDKHIKCPK CGKENFTSIR KFNLMFKTFQ GVTEDASSEI YLRPETAQGI
190 200 210 220 230 240
FVNFKNVQRS SRKKVPFGIG QIGKAFRNEI TPGNFTFRTR EFEQMELEFF CKPGTDLEWF
250 260 270 280 290 300
KYWKDYCWSF LLDLGINKEN LRFRDHSAEE LVFYSKATSD IEYKFPFGWG ELWGVADRTD
310 320 330 340 350 360
YDLKKHMDHS GEDMNYLDPS TNEKYVPYVI EPSLGADRVA LAFLIDAYDE EELEGGDQRI
370 380 390 400 410 420
VLHFHPQIAP IKAAVLPLSK KLSEKALDVY SKISSKFNIE YDETGSIGKR YRRQDEIGTP
430 440 450 460
YCITVDFDTL EDEAVTIRDR DSMSQVRVKI EELEKYLEEK IK