Q977Q3
Gene name |
pfkC |
Protein name |
ADP-specific phosphofructokinase |
Names |
ADP-dependent phosphofructokinase, ADP-Pfk |
Species |
Thermococcus litoralis |
KEGG Pathway |
|
EC number |
2.7.1.146: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q977Q3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q977Q3-F1 | Predicted | AlphaFoldDB |
No variants for Q977Q3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q977Q3 | |||||
No associated diseases with Q977Q3
No regional properties for Q977Q3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q977Q3 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.146 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ADP-specific phosphofructokinase activity | Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| phosphofructokinase activity | Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| fructose metabolic process | The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. |
| glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMEFLKDFQK | MGIYLAYNVN | VDAIVYLNEK | HIESLIKEFG | AENIKKRIDE | YPREINEPLD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FVARLIHALK | TGKPQAVPLV | SYEADKWFNS | RFKYDFERIG | GQVGVIANLL | ANLDFNKVIA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YSPLLGRKQA | EMFVNRDNLL | YPVVENGKLV | LKKPLEAYRE | DDPVKINRIF | EFRAGTKFKL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GDETIEVPYS | GRFIVACRFE | DFARIETSPE | LKPYLPEIGE | MVDGAILSGY | QGLRRYYSDG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KDANYYLRKA | KEDIKLLKKK | KDIKIHVEFA | SIQDRELRKK | VIYNIFPLVD | SVGMDEAEIA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HILSVLGYRE | LSDRIFTYNR | IEDAVLGAKI | LLDELNLEIL | QVHTIYYLMY | ITHNDNPLTE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EELTKSLEVG | TTLAAARAFL | GDIKRPEDVK | VGLNIPFNEK | GEYVKLRFEE | AKAKMRTREY |
| 430 | 440 | 450 | |||
| KIVIIPTRLV | RNPVSTVGLG | DTISAGAFAS | YLSLLKRKE |