Q975N0

PR
Gene name
cbiA
Protein name
Cobyrinate a,c-diamide synthase
Names
Cobyrinic acid a,c-diamide synthetase
Species
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
KEGG Pathway
sto:STK_03890
EC number
6.3.5.11: Carbon--nitrogen ligases with glutamine as amido-N-donor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

169-261 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q975N0

Entry ID Method Resolution Chain Position Source
AF-Q975N0-F1 Predicted AlphaFoldDB

No variants for Q975N0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q975N0

No associated diseases with Q975N0

14 regional properties for Q975N0

Type Name Position InterPro Accession
domain Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 128 - 333 IPR005479-1
domain Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 666 - 867 IPR005479-2
domain Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 420 - 540 IPR005480
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 19 - 33 IPR005483-1
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 48 - 58 IPR005483-2
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 168 - 180 IPR005483-3
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 204 - 223 IPR005483-4
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 239 - 256 IPR005483-5
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 296 - 325 IPR005483-6
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 378 - 396 IPR005483-7
domain Methylglyoxal synthase-like domain 930 - 1062 IPR011607
domain ATP-grasp fold 133 - 327 IPR011761-1
domain ATP-grasp fold 671 - 861 IPR011761-2
domain Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain 936 - 1049 IPR033937

Functions

Description
EC Number 6.3.5.11 Carbon--nitrogen ligases with glutamine as amido-N-donor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
cobyrinic acid a,c-diamide synthase activity Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide.

2 GO annotations of biological process

Name Definition
cobalamin biosynthetic process The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRFPRIIISS DRSNSGKTII SSALMRVLSR KMKVRGFKAG PDFIDPKYHT LAARVPSINL
70 80 90 100 110 120
DLWLMGIEGV KKSLIRYGKG YDIGIIEGVM GLYDGINVNY STYELSEVTK TPIILVVNCS
130 140 150 160 170 180
NVSSTVGAIV KGLKDYRNAR IRGVIFNQIG SETHYNYCKS SIKEVQVLGY IKYDRNFSVP
190 200 210 220 230 240
SRHLGLFTTE DFKETENVLQ SVSKAIEESV DIDKIIEIAN SAEELQEVDE AISNDELDTK
250 260 270 280 290 300
KGIAAIAYDS AFNFYYSENI DLLRYKYQIE FFSPLLNEKI DNPSLIYVGG GYPELHLNEL
310 320 330 340 350 360
EKSSSTIRWI KKEAEKGTKI LAECGGLMYL SKEIIADKSY KMVNLFDISI KAKDKLTIGY
370 380 390 400 410 420
TELDVLSDNI LGRKGEVLRG HEFHVSKAIN LGNDVKFSMK NRIGKGIWEN KDGAIVYNTL
430
ASYSHFHFSS ARGLLSF