Q96X43
Gene name |
URE2 (KLLA0D19624g) |
Protein name |
Protein URE2 |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_D19624g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q96X43
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q96X43-F1 | Predicted | AlphaFoldDB |
No variants for Q96X43
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q96X43 | |||||
No associated diseases with Q96X43
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutathione peroxidase activity | Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O. |
| phosphoprotein binding | Binding to a phosphorylated protein. |
| transcription corepressor activity | A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic sequestering of transcription factor | The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. |
| nitrate assimilation | The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances. |
| protein urmylation | Covalent attachment of the ubiquitin-like protein URM1 to another protein. |
| regulation of nitrogen utilization | Any process that modulates the frequency, rate or extent of nitrogen utilization. |
| response to aluminum ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQQDMQNGGP | GNTISNLSSA | LRQVNLGNSN | TTTDQSNISI | DFNQQQLLEE | ANQGSINAYN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AQQQQQEHLQ | QQAQQQQLHM | QQLQQAQQQQ | AQQQAHQQQQ | QVHQVQHQHV | QQDHMPIGQS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QQQAMYQGPN | PIDSSRITKF | FQNQPMEGYT | LFSHRSAPNG | FKVAIVLSEL | NMHYNTIFLD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FNLGEHRAPE | FVAINPNARV | PALIDHNMEN | LSIWESGAII | LHVVNKHYKE | TGNPLLWSDS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LADQAQINAW | LFFQTSGHAP | MIGQALHFRY | FHSQKVKSAV | DRYTDEVRRV | YGVVEMALAE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RREALIMDLD | SENAAAYSAG | TTPLSQSRFF | DYPVWLVGDK | ITVADLSFVP | WNNVVDRIGI |
| 370 | 380 | ||||
| NIKVEFPEVY | KWTKHMMRRP | AVIKALRGE |