Q96U60

PR
Gene name
kpr-1 (ndc80, B23L21.070, NCU03899)
Protein name
Probable kinetochore protein ndc80
Names
Kinetochore protein 1
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU03899
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

16-183 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q96U60

Entry ID Method Resolution Chain Position Source
AF-Q96U60-F1 Predicted AlphaFoldDB

No variants for Q96U60

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q96U60

No associated diseases with Q96U60

No regional properties for Q96U60

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q96U60

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome, centromere, kinetochore
  • Associated with kinetochores
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Ndc80 complex An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
attachment of mitotic spindle microtubules to kinetochore The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQDSNAGLW SVRRPRETLH GVNLTSGIPA PPSTLKRQST IGTIGTGHGR SLSGRQSLAL
70 80 90 100 110 120
PRPSQPLFQR SSDIGLGSVK RASVHNMNTS QFKPYGTPGS SGIPRSSQEL DRRSSVYRPS
130 140 150 160 170 180
ARPSAVGGGP LAGGHMSFFQ QAPQPAGVPR DPRPLKDRQF QNRIGQELLE YLAKNNFEME
190 200 210 220 230 240
MNHKLSDNFT KSPTQKDFNY LFQWLYHRID PSYRFQKNID QEVPPLLKQL RYPYEKSITK
250 260 270 280 290 300
SQIAAVGGQN WSTFLGLLHW MMQLAQMLEG YARHQYDDAC MEAGVDIAGD QIIFDFLTSA
310 320 330 340 350 360
YQDWLNMDDE AGDEDVERAL QPHVQGMAEA FERSNAKYIQ ELEILEGENA RLLKEIQELE
370 380 390 400 410 420
KSTPDPAILD NHFKIMEEDK IKFEEYNTLA MQRTEKYENR IQVLREELGK LHVELKEAEE
430 440 450 460 470 480
ERRQMQKAVD DQGISMQDID RMTSERERLQ RSIESASQRL EDVKKKVAER EMEASQRLDE
490 500 510 520 530 540
LERLVEKYNT VAYQIGLIPA TAVNAKGKNL ELQVTVNEGT PNFASSMQGV LGPNGQPLGG
550 560 570 580 590 600
VENERLLADS TTGYQPAHIL NLDLRGQVKN TFLALRKEVS ERRKVAMDVM MEDHDLLDRA
610 620 630 640 650 660
KEAIEDKRNE VEALGHRVRA AEEEYEKTKE VTNAQKMASD AQIEKMEKEL AKMRAQLSES
670 680 690 700 710 720
VQLMEQREMN TNIEYEQLTL RANALREELH TETMRMLNDV IKFKMHVQRS LEEYETFVAD
730 740
ELEQELGIDD QEMEDEDTPM ADV