Q96CB5

PR
Gene name
C8orf44
Protein name
Putative uncharacterized protein C8orf44
Names
Species
Homo sapiens (Human)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-159 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q96CB5

Entry ID Method Resolution Chain Position Source
AF-Q96CB5-F1 Predicted AlphaFoldDB

2 variants for Q96CB5

Variant ID(s) Position Change Description Diseaes Association Provenance
rs1909534
VAR_030888
 131 Q>R No UniProt
dbSNP
rs1057463
VAR_030889
 148 F>S No UniProt
dbSNP

No associated diseases with Q96CB5

10 regional properties for Q96CB5

Type Name Position InterPro Accession
domain DNA topoisomerase, type IA, domain 2 107 - 195 IPR003601
domain DNA topoisomerase, type IA, DNA-binding domain 249 - 519 IPR003602
domain TOPRIM domain 1 - 116 IPR006171
domain DNA topoisomerase, type IA, central 75 - 88 IPR013497-1
domain DNA topoisomerase, type IA, central 131 - 567 IPR013497-2
domain DNA topoisomerase, type IA, zn finger 599 - 633 IPR013498
active_site DNA topoisomerase, type IA, active site 286 - 308 IPR023406
repeat Topoisomerase C-terminal repeat 661 - 718 IPR025589-1
repeat Topoisomerase C-terminal repeat 720 - 769 IPR025589-2
domain DNA topoisomerase 1, TOPRIM domain 1 - 128 IPR034149

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRKNESYLNQ PAPPIPIPTL SLMGGCREHF ENHWKGRARW LMPVIPALWE AKAGRSPEVR
70 80 90 100 110 120
SSKPAWPTWR NPIFTKNTKI SQVLELFLNY QSLICALEKQ KRQKGSLAIF CWSFQGGCVS
130 140 150
KRPDVPSLKS QKPKRKRITG RKRLSKGFWS LLFSNLGRF