AiPD: Autoinhibited Protein Database

Q96C34

Gene name	RUNDC1 (LP5161)
Protein name	RUN domain-containing protein 1
Names
Species	Homo sapiens (Human)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

32-108 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

32-108 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q96C34

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q96C34-F1	Predicted				AlphaFoldDB

495 variants for Q96C34

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs864622034 CA350489 RCV000206459	289	G>A	Malignant tumor of prostate [ClinVar]	Yes	ClinGen ClinVar Ensembl dbSNP
rs562961994 CA8588515	3	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs945576436 CA290809288	3	A>V		No	ClinGen TOPMed gnomAD
CA8588516 rs17853899	4	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
VAR_031760 rs17853899 CA290809293	4	V>I		No	ClinGen UniProt ESP ExAC TOPMed dbSNP gnomAD
rs372920205 CA290809301	5	E>*		No	ClinGen ESP TOPMed gnomAD
CA8588517 rs746367589	5	E>V		No	ClinGen ExAC gnomAD
rs199576891 CA290809304	6	A>E		No	ClinGen ExAC TOPMed gnomAD
CA8588518 rs770339301	6	A>T		No	ClinGen ExAC gnomAD
CA8588519 rs199576891	6	A>V		No	ClinGen ExAC TOPMed gnomAD
rs530398987 CA8588520	7	A>S		No	ClinGen 1000Genomes ExAC gnomAD
CA399662083 rs530398987	7	A>T		No	ClinGen 1000Genomes ExAC gnomAD
rs1278647266 CA399662090	7	A>V		No	ClinGen TOPMed gnomAD
CA399662106 rs1187720915	8	A>T		No	ClinGen TOPMed
CA8588521 rs764334670	8	A>V		No	ClinGen ExAC TOPMed gnomAD
CA8588524 rs376633797	9	E>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs1283184177 CA399662126	9	E>G		No	ClinGen gnomAD
CA8588522 rs774457362	9	E>Q		No	ClinGen ExAC gnomAD
rs750311395 CA8588525	10	P>A		No	ClinGen ExAC gnomAD
rs201536677 CA8588526	10	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201536677 CA399662145	10	P>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201536677 CA8588527	10	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8588528 rs753362536	11	V>E		No	ClinGen ExAC gnomAD
rs1191597359 CA399662154	11	V>I		No	ClinGen TOPMed gnomAD
CA290809340 rs1049018389	12	T>M		No	ClinGen gnomAD
CA8588529 rs754479522	13	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1328031750 CA399662231	16	A>D		No	ClinGen gnomAD
rs1567727400 CA399662226	16	A>T		No	ClinGen Ensembl
CA8588531 rs752347491	17	V>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	20	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8588533 rs781518919	23	D>N		No	ClinGen ExAC gnomAD
rs1037379804 CA290809375	24	E>K		No	ClinGen gnomAD
rs746277478 CA8588536	25	E>D		No	ClinGen ExAC TOPMed gnomAD
CA399662355 rs1348131839	25	E>G		No	ClinGen gnomAD
CA399662346 rs1173468563	25	E>K		No	ClinGen TOPMed
CA399662365 rs1567727443	26	E>K		No	ClinGen Ensembl
rs1003348614 CA290809391	27	E>K		No	ClinGen TOPMed
rs749337848 CA8588538	28	E>K		No	ClinGen ExAC gnomAD
CA399662414 rs1211265169	28	E>V		No	ClinGen gnomAD
rs865978432 CA290809406	29	E>G		No	ClinGen Ensembl
rs1033529538 CA290809399	29	E>K		No	ClinGen TOPMed gnomAD
TCGA novel	33	P>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs768630844 CA8588539	33	P>S		No	ClinGen ExAC gnomAD
rs774568055 CA8588540	34	P>L		No	ClinGen ExAC TOPMed gnomAD
CA8588541 rs774568055	34	P>R		No	ClinGen ExAC TOPMed gnomAD
CA399662498 rs1471740481	34	P>S		No	ClinGen TOPMed gnomAD
CA399662496 rs1471740481	34	P>T		No	ClinGen TOPMed gnomAD
CA399662510 rs1461038593	35	C>R		No	ClinGen TOPMed gnomAD
rs773119716 CA8588543	36	E>K		No	ClinGen ExAC gnomAD
rs1317288111 CA399662579	39	R>P		No	ClinGen TOPMed
CA8588544 rs369316147	39	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA8588545 rs766304000	41	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1342244925 CA399662633	42	P>S		No	ClinGen gnomAD
rs1334282946 CA399662644	43	V>L		No	ClinGen TOPMed gnomAD
rs1334282946 CA399662643	43	V>M		No	ClinGen TOPMed gnomAD
CA399662668 rs1333678635	44	G>A		No	ClinGen gnomAD
rs1333678635 CA399662665	44	G>E		No	ClinGen gnomAD
CA8588547 rs759031445	44	G>R		No	ClinGen ExAC TOPMed gnomAD
CA399662662 rs759031445	44	G>W		No	ClinGen ExAC TOPMed gnomAD
rs752259638 CA8588549	46	V>M		No	ClinGen ExAC TOPMed gnomAD
CA399662742 rs1195097040	49	A>D		No	ClinGen gnomAD
CA8588551 rs777439485	51	P>L		No	ClinGen ExAC TOPMed gnomAD
rs750745524 CA8588552	52	G>E		No	ClinGen ExAC gnomAD
rs1445196200 CA399662801	54	T>A		No	ClinGen TOPMed
CA399662806 rs1353113393	54	T>I		No	ClinGen TOPMed gnomAD
CA399662857 rs1474982417	57	L>F		No	ClinGen gnomAD
rs144065038 CA8588553	60	A>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs144065038 CA399662914	60	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA399662916 rs1459016017	61	T>A		No	ClinGen TOPMed
rs1374810891 CA399662924	61	T>R		No	ClinGen gnomAD
rs1167915605 CA399662935	62	A>V		No	ClinGen gnomAD
rs1417066993 CA399662941	63	E>K		No	ClinGen gnomAD
CA399662980 rs1354460517	64	E>D		No	ClinGen gnomAD
CA399662966 rs1313838094	64	E>Q		No	ClinGen TOPMed gnomAD
rs1393880124 CA399662990	65	P>T		No	ClinGen TOPMed gnomAD
CA290809518 rs1043060947	66	G>S		No	ClinGen TOPMed
rs1381929739 CA399663016	67	A>T		No	ClinGen TOPMed
CA399663026 rs1297116664	67	A>V		No	ClinGen gnomAD
CA8588554 rs28584166	68	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8588555 rs749764412	69	P>L		No	ClinGen ExAC gnomAD
CA399663069 rs1249601042	70	G>A		No	ClinGen TOPMed gnomAD
rs1249601042 CA399663067	70	G>D		No	ClinGen TOPMed gnomAD
rs974858698 CA290809538	72	P>R		No	ClinGen Ensembl
CA399663110 rs1597749619	73	P>R		No	ClinGen Ensembl
CA399663115 rs1485477871	74	D>N		No	ClinGen gnomAD
CA399663121 rs1485477871	74	D>Y		No	ClinGen gnomAD
rs1264118777 CA399663160	76	P>L		No	ClinGen gnomAD
CA399663183 rs1192535259	78	R>Q		No	ClinGen gnomAD
CA399663224 rs1236147947	81	R>L		No	ClinGen gnomAD
CA399663258 rs1244323715	84	R>Q		No	ClinGen TOPMed
CA399663292 rs1317807094	87	R>W		No	ClinGen TOPMed
CA399663297 rs1437080213	88	R>W		No	ClinGen TOPMed gnomAD
rs1385431323 CA399663352	91	D>E		No	ClinGen TOPMed gnomAD
rs900259583 CA290809558	92	S>W		No	ClinGen TOPMed
CA399663447 rs1464234215	98	S>F		No	ClinGen gnomAD
CA399663586 rs1373132698	107	R>C		No	ClinGen gnomAD
CA399663611 rs1234862261	109	R>P		No	ClinGen gnomAD
rs1395545589 CA399663621	110	Q>*		No	ClinGen TOPMed
CA399663640 rs1302423305	111	V>M		No	ClinGen gnomAD
rs1217663502 CA399663655	112	V>L		No	ClinGen gnomAD
rs1200917007 CA399663672	113	R>G		No	ClinGen TOPMed
rs1200917007 CA399663670	113	R>S		No	ClinGen TOPMed
CA399663685 rs1486300295 CA399663682	114	G>R		No	ClinGen gnomAD
CA399663710 rs1246212268	115	A>E		No	ClinGen gnomAD
rs773602396 CA8588560	115	A>T		No	ClinGen ExAC gnomAD
rs1246212268 CA399663705	115	A>V		No	ClinGen gnomAD
rs1431432164 CA399663725	116	P>L		No	ClinGen TOPMed
rs1455976794 CA399663738	117	A>E		No	ClinGen gnomAD
CA399663769 rs1395004204	119	Q>*		No	ClinGen gnomAD
rs760501540 CA8588561	120	Q>H		No	ClinGen ExAC gnomAD
CA399663789 rs1449904351	120	Q>R		No	ClinGen gnomAD
CA290809584 rs550864158	121	R>G		No	ClinGen 1000Genomes
CA399663805 rs770648532	121	R>H		No	ClinGen ExAC TOPMed gnomAD
CA8588562 rs770648532	121	R>L		No	ClinGen ExAC TOPMed gnomAD
rs1345458782 CA399663815	122	L>F		No	ClinGen gnomAD
CA399663828 rs1452550054	123	L>P		No	ClinGen gnomAD
rs1452550054 CA399663830	123	L>Q		No	ClinGen gnomAD
CA399663835 rs1441002706	124	R>Q		No	ClinGen gnomAD
rs1395954253 CA399663832	124	R>W		No	ClinGen gnomAD
CA399663841 rs1302653478	125	E>K		No	ClinGen gnomAD
CA399663842 rs1302653478	125	E>Q		No	ClinGen gnomAD
TCGA novel	125	E>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1376358453 CA399663862	126	L>V		No	ClinGen gnomAD
rs1488721988 CA399663884	127	E>G		No	ClinGen TOPMed
rs759373874 CA8588564	130	A>T		No	ClinGen ExAC gnomAD
rs765265688 CA8588565	132	R>C		No	ClinGen ExAC TOPMed gnomAD
CA399664073 rs1487772251	138	L>P		No	ClinGen gnomAD
CA8588568 rs552222	138	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1010650507 CA290809648	141	E>K		No	ClinGen Ensembl
rs1418156446 CA399664131	142	G>R		No	ClinGen gnomAD
rs751226206 CA8588570	143	P>L		No	ClinGen ExAC gnomAD
rs766648925 CA8588572	145	D>N		No	ClinGen ExAC gnomAD
TCGA novel	145	D>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	146	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA399664217 rs1324600452	147	A>S		No	ClinGen gnomAD
CA399664224 rs1348085641	147	A>V		No	ClinGen gnomAD
CA399664228 rs1597750268	148	S>G		No	ClinGen Ensembl
rs754286789 CA8588573	150	E>A		No	ClinGen ExAC TOPMed gnomAD
CA399664293 rs1243392119	151	G>D		No	ClinGen gnomAD
CA399664307 rs1372256970	152	D>Y		No	ClinGen gnomAD
rs1286753903 CA399664332	153	G>E		No	ClinGen gnomAD
rs1234017320 CA399664341	154	L>M		No	ClinGen gnomAD
rs1289185157 CA399664352	155	P>S		No	ClinGen gnomAD
CA8588575 rs755420359	156	G>E		No	ClinGen ExAC TOPMed gnomAD
CA399664370 rs1320463144	156	G>R		No	ClinGen gnomAD
CA399664396 rs1259233124	157	D>E		No	ClinGen TOPMed gnomAD
CA399664392 rs1180444666	157	D>G		No	ClinGen gnomAD
rs779605527 CA8588576	157	D>H		No	ClinGen ExAC gnomAD
CA399664382 rs779605527	157	D>N		No	ClinGen ExAC gnomAD
CA290809697 rs781273982	160	W>*		No	ClinGen TOPMed gnomAD
CA8588580 rs747204117	160	W>*		No	ClinGen ExAC TOPMed gnomAD
rs1708875 CA8588579	160	W>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA399664430 rs747204117	160	W>L		No	ClinGen ExAC TOPMed gnomAD
VAR_031761 CA8588578 rs1708875	160	W>R		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA399664452 rs1478201702	162	R>G		No	ClinGen TOPMed
rs771239383 CA8588581	162	R>Q		No	ClinGen ExAC
CA8588582 rs776264058	163	G>S		No	ClinGen ExAC gnomAD
rs1191773713 CA399664474	163	G>V		No	ClinGen TOPMed
CA290809725 rs760923216	165	D>E		No	ClinGen TOPMed
rs1357634094 CA399664509	166	Q>*		No	ClinGen gnomAD
CA399666513 rs1567730964	169	Q>E		No	ClinGen Ensembl
TCGA novel	169	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1567730974 CA399666532	171	K>R		No	ClinGen Ensembl
CA8588600 rs781505914	172	Q>R		No	ClinGen ExAC gnomAD
CA399666558 CA399666559 rs369497685	173	E>D		No	ClinGen ESP TOPMed gnomAD
CA8588601 rs745600074	173	E>K		No	ClinGen ExAC TOPMed gnomAD
CA399666555 rs1432982610	173	E>V		No	ClinGen gnomAD
rs769587764 CA8588602	174	R>C		No	ClinGen ExAC TOPMed gnomAD
rs34886583 COSM1383487 CA8588603	174	R>H	large_intestine [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs769587764 CA399666561	174	R>S		No	ClinGen ExAC TOPMed gnomAD
CA399666576 rs1273398453	175	L>Q		No	ClinGen gnomAD
rs1567731001 CA399666615	178	Q>*		No	ClinGen Ensembl
rs377394528 CA8588604	182	Q>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs377394528 CA290812863	182	Q>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA290812868 rs200463952	182	Q>R		No	ClinGen 1000Genomes
CA290812872 rs766280856	186	I>V		No	ClinGen TOPMed gnomAD
CA8588605 rs768638303	187	L>V		No	ClinGen ExAC gnomAD
CA8588608 rs370774883	190	K>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs772942848 CA8588609	195	D>N		No	ClinGen ExAC gnomAD
CA8588611 rs765705110	198	T>M		No	ClinGen ExAC gnomAD
rs1382829140 CA399666911	204	G>S		No	ClinGen Ensembl
rs763528529 CA8588613	205	S>N		No	ClinGen ExAC gnomAD
CA399666957 rs1597757073	207	D>A		No	ClinGen Ensembl
rs199867848 CA8588614	208	S>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	210	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA399667011 rs1322000932	211	Q>R		No	ClinGen gnomAD
CA8588617 rs371790855	213	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1287387316 CA399667045	214	V>L		No	ClinGen gnomAD
CA8588619 rs756395019	219	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs750660231 CA8588618	219	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1272286639 CA399667268	220	V>L		No	ClinGen TOPMed
CA399667299 rs1357171445	222	I>M		No	ClinGen TOPMed
CA8588634 rs767630340	223	D>G		No	ClinGen ExAC gnomAD
rs1190246248 CA399667302	223	D>N		No	ClinGen gnomAD
TCGA novel	223	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8588635 rs750524899	225	L>F		No	ClinGen ExAC TOPMed gnomAD
rs1375318685 CA399667350	227	K>N		No	ClinGen gnomAD
rs368796436 CA8588636	227	K>T		No	ClinGen ExAC TOPMed gnomAD
rs1382423338 CA399667385	230	D>E		No	ClinGen TOPMed
CA8588637 rs780295121	230	D>N		No	ClinGen ExAC gnomAD
rs902124755 CA290813793	232	N>H		No	ClinGen TOPMed
CA8588638 rs753592981	232	N>S		No	ClinGen ExAC gnomAD
rs996805079 CA290813805	234	N>I		No	ClinGen TOPMed
CA290813807 rs55637973	236	D>G		No	ClinGen Ensembl
rs1353232384 CA399667447	236	D>N		No	ClinGen TOPMed
rs546662271 CA8588639	238	S>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA399667477 rs1375862340	238	S>T		No	ClinGen gnomAD
CA399667496 rs1405391230	240	L>V		No	ClinGen TOPMed
CA399667510 rs1415367575	241	S>C		No	ClinGen TOPMed
CA399667538 rs1393831220	244	E>K		No	ClinGen gnomAD
CA8588640 rs778661306	246	R>C		No	ClinGen ExAC TOPMed gnomAD
CA8588641 rs748123180	246	R>H		No	ClinGen ExAC TOPMed gnomAD
CA8588642 rs757868579	247	Q>E		No	ClinGen ExAC TOPMed gnomAD
rs375224265 CA8588643	247	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs149556177 CA8588645	248	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs371936857 CA8588646	248	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs371936857 CA290813832	248	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1452185201 CA399667588	249	V>L		No	ClinGen TOPMed
rs749603489 CA8588647	250	D>G		No	ClinGen ExAC gnomAD
rs769067964 CA399667613	251	A>G		No	ClinGen ExAC gnomAD
CA8588648 rs769067964	251	A>V		No	ClinGen ExAC gnomAD
rs774644242 CA8588649	254	A>G		No	ClinGen ExAC gnomAD
TCGA novel	254	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA399667637 rs1292136662	255	Q>E		No	ClinGen TOPMed
rs1188562656 CA399667640	255	Q>R		No	ClinGen gnomAD
rs762368564 CA399667650	256	I>M		No	ClinGen ExAC TOPMed gnomAD
rs1243950057 CA399667648	256	I>T		No	ClinGen TOPMed
CA399667654 rs1279444210	257	V>A		No	ClinGen TOPMed
rs202076807 CA8588651	257	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1177200803 CA399667656	258	N>H		No	ClinGen gnomAD
rs773245859 CA8588652	258	N>S		No	ClinGen ExAC TOPMed gnomAD
CA399667668 rs1464183022	259	P>A		No	ClinGen gnomAD
rs760776472 CA8588653	261	R>*		No	ClinGen ExAC TOPMed gnomAD
rs760776472 CA399667686	261	R>G		No	ClinGen ExAC TOPMed gnomAD
CA8588654 rs568593311	261	R>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs568593311 CA399667689	261	R>P		No	ClinGen 1000Genomes ExAC gnomAD
rs961750871 CA290813913	263	K>R		No	ClinGen TOPMed gnomAD
rs1423524841 CA399667729	265	Q>R		No	ClinGen TOPMed
rs1597758635 CA399667766	268	E>D		No	ClinGen Ensembl
rs1417043439 CA399667809	272	T>I		No	ClinGen TOPMed
rs1597758650 CA399667815	273	Q>E		No	ClinGen Ensembl
TCGA novel	275	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA399667840 rs1406986490	275	R>G		No	ClinGen TOPMed
CA399667850 rs1311841469	276	D>H		No	ClinGen gnomAD
rs375923988 CA8588660	277	L>F		No	ClinGen ESP ExAC gnomAD
TCGA novel	279	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA290813944 rs986025728	279	M>K		No	ClinGen Ensembl
rs376014187 CA8588661	282	N>S		No	ClinGen ExAC gnomAD
CA8588662 rs750828455	283	F>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	284	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1472033832 CA399669420	287	E>K		No	ClinGen gnomAD
CA399669460 rs1339573645	288	V>A		No	ClinGen TOPMed gnomAD
rs146074807 CA8588682	288	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA8588681 rs146074807	288	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA8588684 rs755761147	290	S>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA399669510 rs1164072533	290	S>N		No	ClinGen gnomAD
rs1166896440 COSM561092 CA399669573	293	Q>R	lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA8588686 rs756553386	294	T>I		No	ClinGen ExAC gnomAD
CA399669611 rs1426225571	295	G>D		No	ClinGen Ensembl
rs529320647 CA8588687	296	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs772338809 CA8588688 CA8588689	297	G>R		No	ClinGen ExAC gnomAD
rs747514103 CA8588690	298	H>Y		No	ClinGen ExAC gnomAD
rs771489843 CA8588691	300	E>Q		No	ClinGen ExAC gnomAD
CA8588692 rs776674954	301	C>S		No	ClinGen ExAC gnomAD
rs1289848937 CA399669790	303	A>G		No	ClinGen TOPMed gnomAD
rs1289848937 CA399669788	303	A>V		No	ClinGen TOPMed gnomAD
CA8588694 rs375924857	304	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA399669813 rs1206579673	304	G>V		No	ClinGen TOPMed
CA8588695 rs775585211	307	T>I		No	ClinGen ExAC gnomAD
CA399669934 rs1482526966	310	G>S		No	ClinGen gnomAD
CA399669996 rs1202671144	312	S>R		No	ClinGen gnomAD
CA399670031 rs1567732349	315	G>R		No	ClinGen Ensembl
rs763974387 CA399670077	317	S>I		No	ClinGen ExAC TOPMed gnomAD
rs763974387 CA8588697	317	S>N		No	ClinGen ExAC TOPMed gnomAD
CA8588698 rs200178797	319	T>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1430181673 CA399670171	322	G>E		No	ClinGen gnomAD
CA399670176 rs1244176530	323	N>D		No	ClinGen TOPMed
CA399670188 rs1168998443	324	S>G		No	ClinGen TOPMed gnomAD
CA8588717 rs761730621	330	D>N		No	ClinGen ExAC TOPMed gnomAD
rs1330674284 CA399670442	331	V>M		No	ClinGen TOPMed gnomAD
rs1384276302 CA399670469	332	K>E		No	ClinGen gnomAD
CA290818775 rs553638883	334	V>A		No	ClinGen 1000Genomes gnomAD
CA399670538 rs572946898	335	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8588719 rs572946898	335	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8588718 rs199952607 COSM1581617	335	R>W	Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1315463552 CA399670564	336	E>D		No	ClinGen TOPMed
CA8588720 rs760167480	336	E>K		No	ClinGen ExAC gnomAD
CA8588721 rs765805859	337	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	339	L>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1597759839 CA399670640	340	H>P		No	ClinGen Ensembl
rs1465576622 CA399670684	341	L>R		No	ClinGen TOPMed
rs757628851 CA8588726	342	M>K		No	ClinGen ExAC TOPMed gnomAD
CA399670711 rs200561980	343	R>G		No	ClinGen TOPMed gnomAD
CA399670718 rs374188538	343	R>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8588727 rs374188538	343	R>Q	Variant assessed as Somatic; 4.635e-05 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA290818799 rs200561980	343	R>W		No	ClinGen TOPMed gnomAD
rs746353875 CA399670726	344	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA8588728 rs746353875	344	R>G		No	ClinGen ExAC gnomAD
CA290818819 COSM561091 rs756700931	345	A>S	lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA8588729 rs756700931	345	A>T		No	ClinGen ExAC TOPMed gnomAD
CA8588730 rs779974943	345	A>V		No	ClinGen ExAC TOPMed gnomAD
CA399670792 rs1228503975	347	A>D		No	ClinGen gnomAD
CA399670773 rs1351915551	347	A>S		No	ClinGen gnomAD
CA399670814 rs774736859	348	V>L		No	ClinGen ExAC TOPMed gnomAD
CA8588733 rs774736859	348	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1211636291 CA399670860	350	Q>H		No	ClinGen gnomAD
rs747894928 CA8588734	352	F>L		No	ClinGen ExAC gnomAD
CA8588735 rs771998451	353	A>P		No	ClinGen ExAC gnomAD
CA8588737 rs760518488	355	S>R		No	ClinGen ExAC TOPMed gnomAD
CA290818851 rs572766174	356	Q>*		No	ClinGen Ensembl
rs759857691 CA290818854	358	G>A		No	ClinGen Ensembl
rs867685651 CA290818857	360	A>V		No	ClinGen Ensembl
rs1487230204 CA399671150	363	Q>E		No	ClinGen TOPMed gnomAD
TCGA novel	363	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA399671175 rs1567732682	364	I>F		No	ClinGen Ensembl
rs1340979240 CA399671188	364	I>M		No	ClinGen TOPMed
CA8588738 rs377624220	366	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA399671264 rs1183008541	368	L>P		No	ClinGen gnomAD
CA399671258 rs1247837882	368	L>V		No	ClinGen TOPMed
CA290818860 rs998085368	369	W>*		No	ClinGen TOPMed
rs759081997 CA8588740	370	Q>H		No	ClinGen ExAC gnomAD
rs1165566728 CA399671447	377	D>Y		No	ClinGen gnomAD
CA8588741 rs764807787	378	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA8588742 rs752347435	380	P>L		No	ClinGen ExAC TOPMed gnomAD
CA399671542 rs1321942859	383	K>N		No	ClinGen TOPMed gnomAD
rs1597760044 CA399671581	386	E>G		No	ClinGen Ensembl
rs61995866 CA8588743	386	E>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1597760056 CA399671596	387	V>G		No	ClinGen Ensembl
rs767757645 CA8588744	387	V>M		No	ClinGen ExAC gnomAD
rs1597760064 CA399671607	388	S>A		No	ClinGen Ensembl
CA399671627 rs1597760077	389	V>G		No	ClinGen Ensembl
CA8588745 rs544350931	392	V>L		No	ClinGen 1000Genomes ExAC gnomAD
rs780641883 CA8588747	396	A>T		No	ClinGen ExAC gnomAD
VAR_031762 rs17857183 CA290818897	397	L>M		No	ClinGen UniProt Ensembl dbSNP
CA8588748 rs749340594	397	L>S		No	ClinGen ExAC gnomAD
rs1276442771 CA399671777	399	Q>E		No	ClinGen gnomAD
rs1567732870 CA399671790	399	Q>H		No	ClinGen Ensembl
CA8588751 rs779218299	401	P>L		No	ClinGen ExAC gnomAD
CA399671842 rs1251340523	402	H>P		No	ClinGen gnomAD
CA8588752 rs748365795	403	D>G		No	ClinGen ExAC
CA399671919 rs1597760154	407	T>P		No	ClinGen Ensembl
CA399671958 rs1164483300	409	A>V		No	ClinGen TOPMed
rs746867708 CA8588756	413	D>V		No	ClinGen ExAC
CA399672050 rs1597760182	416	L>P		No	ClinGen Ensembl
rs770721701 CA8588757	418	G>C		No	ClinGen ExAC gnomAD
rs776639410 CA8588758	418	G>D		No	ClinGen ExAC gnomAD
rs1307080888 CA399672096	419	K>M		No	ClinGen gnomAD
CA399672126 rs1383791435	421	E>K		No	ClinGen TOPMed
CA8588759 rs376046963	423	T>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs376046963 CA399672158	423	T>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs1016355447 CA290818938	423	T>S		No	ClinGen TOPMed
TCGA novel	424	M>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA290818939 rs541380741	424	M>V		No	ClinGen TOPMed gnomAD
rs1242438968 CA399672229	427	R>Q		No	ClinGen gnomAD
rs764717095 CA8588760	427	R>W		No	ClinGen ExAC TOPMed gnomAD
rs367817542 CA8588762	431	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1274236668 CA399672307	433	A>T		No	ClinGen TOPMed gnomAD
rs761132618 CA8588765	434	V>M		No	ClinGen ExAC gnomAD
rs766728617 CA8588766	436	D>N		No	ClinGen ExAC TOPMed gnomAD
CA399672354 rs61995864	437	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA399672394 rs1597760325	440	H>P		No	ClinGen Ensembl
rs758523797 CA8588771	444	A>V		No	ClinGen ExAC gnomAD
CA8588773 rs746737893	447	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs770777568 CA8588774	449	M>I		No	ClinGen ExAC gnomAD
rs1567733152 CA399672547	452	V>I		No	ClinGen Ensembl
rs993120103 CA290818981	453	M>L		No	ClinGen TOPMed gnomAD
CA290818987 rs368096797	453	M>T		No	ClinGen ESP TOPMed
rs993120103 CA399672556	453	M>V		No	ClinGen TOPMed gnomAD
CA8588775 rs781026704	454	A>V		No	ClinGen ExAC TOPMed gnomAD
CA8588776 rs745804067	455	P>S		No	ClinGen ExAC gnomAD
rs774960270 CA399672586	456	I>L		No	ClinGen ExAC gnomAD
rs774960270 CA8588778	456	I>V		No	ClinGen ExAC gnomAD
rs200110770 CA290818995	458	C>G		No	ClinGen Ensembl
CA399672641 rs1256797635	461	P>S		No	ClinGen gnomAD
rs1394614106 CA399672649	462	A>T		No	ClinGen TOPMed gnomAD
rs745626505 CA8588781	465	S>L		No	ClinGen ExAC TOPMed gnomAD
CA290819023 rs200042329	467	P>S		No	ClinGen gnomAD
rs760891071 CA8588782	468	E>K		No	ClinGen ExAC TOPMed gnomAD
CA8588784 rs775175952	470	M>T		No	ClinGen ExAC TOPMed gnomAD
rs769581002 CA8588783	470	M>V		No	ClinGen ExAC
CA399672739 rs1567733237	471	H>D		No	ClinGen Ensembl
rs760086639 CA8588785	472	P>L		No	ClinGen ExAC gnomAD
CA399672815 rs1456586259	477	V>I		No	ClinGen gnomAD
rs1286904779 CA399672833	478	K>N		No	ClinGen TOPMed gnomAD
TCGA novel	479	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	479	Y>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA399672851 rs1369537450	480	Y>D		No	ClinGen gnomAD
rs140037579 CA8588789	481	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs370262164 CA399672905	484	N>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8588792 rs780936816	485	G>S		No	ClinGen ExAC gnomAD
rs745714064 CA8588793	485	G>V		No	ClinGen ExAC TOPMed gnomAD
CA8588794 rs769671401	486	R>C		No	ClinGen ExAC TOPMed gnomAD
rs779998361 CA8588795	486	R>H		No	ClinGen ExAC TOPMed gnomAD
CA399672942 rs1489697525	488	Y>C		No	ClinGen TOPMed gnomAD
CA8588797 COSM1224394 rs768225556	489	V>A	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA399672949 rs1266266425	489	V>M		No	ClinGen gnomAD
rs773790878 CA8588798	492	P>S		No	ClinGen ExAC gnomAD
rs771660205 CA8588800 COSM284722	494	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA8588799 rs761520902	494	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1156897611 CA399672998	496	L>V		No	ClinGen gnomAD
CA399673007 rs1292684683	497	S>C		No	ClinGen TOPMed gnomAD
CA399673008 rs1292684683	497	S>F		No	ClinGen TOPMed gnomAD
CA399673004 rs1458250743	497	S>T		No	ClinGen gnomAD
rs1448457413 CA399673020	499	S>F		No	ClinGen TOPMed
CA8588803 rs765796687	501	A>T		No	ClinGen ExAC gnomAD
CA399673048 rs1290442380	504	V>I		No	ClinGen gnomAD
CA8588804 rs776141526	505	T>A		No	ClinGen ExAC gnomAD
rs763431743 CA399673056	505	T>K		No	ClinGen ExAC TOPMed gnomAD
CA8588805 rs763431743	505	T>M		No	ClinGen ExAC TOPMed gnomAD
CA399673057 rs763431743	505	T>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	506	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767751816 CA8588809	507	G>D		No	ClinGen ExAC gnomAD
rs145831322 CA8588808	507	G>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs145831322 CA8588807	507	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1420922726 CA399673068	508	T>A		No	ClinGen TOPMed gnomAD
rs372331738 CA290819119	508	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs372331738 CA8588810	508	T>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA399673071 rs1597760905	509	V>I		No	ClinGen Ensembl
rs74586760 CA8588811	513	K>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8588815 rs527942295	516	L>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs527942295 CA8588813	516	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8588817 rs747658188	517	L>V		No	ClinGen ExAC gnomAD
CA8588818 rs773027462	519	A>T		No	ClinGen ExAC gnomAD
rs746163891 CA8588819	520	I>L		No	ClinGen ExAC gnomAD
rs770273376 CA8588820	522	M>V		No	ClinGen ExAC TOPMed gnomAD
rs889665334 CA290819189	523	V>L		No	ClinGen TOPMed gnomAD
CA399673158 rs889665334	523	V>M		No	ClinGen TOPMed gnomAD
rs768120712 CA399673178	526	E>G		No	ClinGen ExAC gnomAD
CA8588821 rs768120712	526	E>V		No	ClinGen ExAC gnomAD
CA290819202 rs1007559890	527	H>R		No	ClinGen TOPMed
rs764559984 CA8588823	528	D>E		No	ClinGen ExAC TOPMed gnomAD
CA399673192 rs1597761070	528	D>G		No	ClinGen Ensembl
rs1441602801 CA399673188	528	D>H		No	ClinGen gnomAD
CA8588824 rs774442115	531	K>M		No	ClinGen ExAC TOPMed gnomAD
rs761831894 CA8588825 COSM1679849	532	R>C	Variant assessed as Somatic; 0.0 impact. haematopoietic_and_lymphoid_tissue [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs767660129 CA8588826	532	R>H		No	ClinGen ExAC TOPMed gnomAD
CA399673218 rs767660129	532	R>L		No	ClinGen ExAC TOPMed gnomAD
rs756385044 CA8588828	533	S>G		No	ClinGen ExAC TOPMed gnomAD
rs766156837 CA8588829	534	A>T		No	ClinGen ExAC gnomAD
CA290819259 rs200217728	534	A>V		No	ClinGen 1000Genomes
rs754919339 CA8588831	536	S>*		No	ClinGen ExAC gnomAD
rs1196530419 CA399673241	536	S>A		No	ClinGen TOPMed
rs1196530419 CA399673240	536	S>P		No	ClinGen TOPMed
rs369376117 CA290819292	540	A>D		No	ClinGen TOPMed gnomAD
rs369376117 CA290819275	540	A>V		No	ClinGen TOPMed gnomAD
CA399673272 rs1241179847	541	L>V		No	ClinGen gnomAD
TCGA novel	542	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1168943624 CA399673280	542	V>L		No	ClinGen gnomAD
CA8588834 rs757983154	544	M>I		No	ClinGen ExAC gnomAD
CA8588835 rs375833434	546	L>M		No	ClinGen ESP ExAC gnomAD
CA8588836 rs746659117	547	N>K		No	ClinGen ExAC gnomAD
rs770751462 CA8588837	550	R>C		No	ClinGen ExAC TOPMed gnomAD
CA8588838 rs147773660	550	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs141180839 CA8588839	553	S>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8588840 rs769168134	554	W>C		No	ClinGen ExAC gnomAD
CA399673358 rs1437755576	554	W>L		No	ClinGen gnomAD
rs774726247 CA8588841	555	V>L		No	ClinGen ExAC gnomAD
rs1597761325 CA399673369	556	N>T		No	ClinGen Ensembl
rs960236076 CA290819401	557	L>V		No	ClinGen TOPMed
rs1212515387 CA399673383	558	I>T		No	ClinGen gnomAD
rs1597761366 CA399673408	562	G>R		No	ClinGen Ensembl
CA399673414 rs1241228093	563	S>T		No	ClinGen gnomAD
rs1188985115 CA399673420	564	L>V		No	ClinGen gnomAD
TCGA novel	565	I>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8588844 rs773346413	565	I>V		No	ClinGen ExAC gnomAD
rs147605440 CA8588846	566	E>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs3744241 CA8588845 VAR_051328	566	E>K		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
rs753619133 CA8588847	567	P>T		No	ClinGen ExAC gnomAD
CA399673452 rs1472426223	569	Y>H		No	ClinGen TOPMed
rs1175742781 CA399673460	570	Q>E		No	ClinGen gnomAD
rs1233426866 CA399673522	578	T>A		No	ClinGen TOPMed
rs759277627 CA8588848	578	T>I		No	ClinGen ExAC gnomAD
rs766700541 CA8588849	584	L>F		No	ClinGen ExAC TOPMed gnomAD
CA399673573 rs1204717759	585	N>K		No	ClinGen TOPMed
CA399673576 rs1326274225	586	L>V		No	ClinGen TOPMed gnomAD
CA8588850 rs752585544	587	L>V		No	ClinGen ExAC gnomAD
CA8588851 rs375753180	589	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA8588852 rs369271006	589	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs113828381 CA290819488	592	S>G		No	ClinGen Ensembl
CA8588853 rs751166538	597	L>I		No	ClinGen ExAC gnomAD
CA399673660 rs1331136863	599	V>I		No	ClinGen gnomAD
CA399673676 rs1283456748	601	L>Q		No	ClinGen gnomAD
rs780741452 CA8588855	601	L>V		No	ClinGen ExAC gnomAD
CA399673679 rs1177799441	602	A>S		No	ClinGen TOPMed gnomAD
rs1597761597 CA399673683	603	V>M		No	ClinGen Ensembl
CA8588856 rs749602274	604	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA8588857 rs768916891	604	R>H		No	ClinGen ExAC TOPMed gnomAD
rs1248696783 CA399673695	605	Q>*		No	ClinGen gnomAD
rs1405168306 CA399673700	605	Q>H		No	ClinGen TOPMed
CA399673724 rs1427372248	609	I>F		No	ClinGen TOPMed gnomAD
CA399673725 rs1427372248	609	I>V		No	ClinGen TOPMed gnomAD
CA399673750 rs1179194696	612	A>G		No	ClinGen TOPMed gnomAD
CA8588860 rs758033721	613	F>I		No	ClinGen ExAC TOPMed gnomAD
CA399673757 rs1430491505	613	F>L		No	ClinGen gnomAD
rs1159705828 CA399673759	614	F>R		No	ClinGen gnomAD

No associated diseases with Q96C34

1 regional properties for Q96C34

Type	Name	Position	InterPro Accession
domain	RUN domain	421 - 602	IPR004012

Functions

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

No GO annotations of cellular component

Name	Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name	Definition
GTPase activator activity	Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

2 GO annotations of biological process

Name	Definition
activation of GTPase activity	Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
in utero embryonic development	The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MAAVEAAAEP	VTVVAAVGPK	AKDEEEEEEE	PLPPCEAVRW	APVGAVAEAR	PGATAFLEEA
70	80	90	100	110	120
TAEEPGAAPG	SPPDSPGRTL	RRLRAERRRL	DSALLALSSH	FAQVQFRLRQ	VVRGAPAEQQ
130	140	150	160	170	180
RLLRELEDFA	FRGCPHVLGY	EGPGDPASDE	GDGLPGDRPW	LRGEDQSEQE	KQERLETQRE
190	200	210	220	230	240
KQKELILQLK	TQLDDLETFA	YQEGSYDSLP	QSVVLERQRV	IIDELIKKLD	MNLNEDISSL
250	260	270	280	290	300
STEELRQRVD	AAVAQIVNPA	RVKEQLVEQL	KTQIRDLEMF	INFIQDEVGS	PLQTGGGHCE
310	320	330	340	350	360
CKAGGKTGNG	CSRTGSSRTP	PGNSKTKAED	VKKVRETGLH	LMRRALAVLQ	IFAVSQFGCA
370	380	390	400	410	420
TGQIPPTLWQ	RVQADRDYSP	LLKRLEVSVD	RVKQLALRQQ	PHDHVITSAN	LQDLSLGGKD
430	440	450	460	470	480
ELTMAVRKEL	TVAVRDLLAH	GLYASSPGMS	LVMAPIACLL	PAFSSAPEAM	HPWELFVKYY
490	500	510	520	530	540
HAKNGRAYVE	SPARKLSQSF	ALPVTGGTVV	TPKQSLLTAI	HMVLTEHDPF	KRSADSELKA
550	560	570	580	590	600
LVCMALNEQR	LVSWVNLICK	SGSLIEPHYQ	PWSYMAHTGF	ESALNLLSRL	SSLKFSLPVD
610
LAVRQLKNIK	DAF