Q96563

PR
Gene name
HEMA2
Protein name
Glutamyl-tRNA reductase 2
Names
GluTR
Species
Hordeum vulgare (Barley)
KEGG Pathway
EC number
1.2.1.70: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

355-465 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q96563

Entry ID Method Resolution Chain Position Source
AF-Q96563-F1 Predicted AlphaFoldDB

No variants for Q96563

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q96563

No associated diseases with Q96563

4 regional properties for Q96563

Type Name Position InterPro Accession
domain Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase 185 - 326 IPR006151
domain Glutamyl-tRNA reductase, N-terminal 19 - 169 IPR015895
domain Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain 340 - 445 IPR015896
conserved_site Glutamyl-tRNA reductase, conserved site 112 - 135 IPR018214

Functions

Description
EC Number 1.2.1.70 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

2 GO annotations of molecular function

Name Definition
glutamyl-tRNA reductase activity Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.
NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.

2 GO annotations of biological process

Name Definition
chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
protoporphyrinogen IX biosynthetic process The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
QFKISADRYI KEKSSIAVIG LSVHTAPVDM REKLAVAEEL WPRAISELTS LNHIEEAAVL
70 80 90 100 110 120
STCNRMEIYV VALSWNRGIR EVVDWMSKKS GIPASELREH LFMLRDSGAT RHLFEVSAGL
130 140 150 160 170 180
DSLVLGEGQI LAQVKQVVRN GQNSGGLGKN IDRMFKDAIT AGKRARCETN ISAGAVSVSS
190 200 210 220 230 240
AAVELAMMKL PKSECLSARM LLIGAGKMGK LVVKHLIAKG CKKVVVVNRS VERVDAIREE
250 260 270 280 290 300
MKDIEIVYRP LTEMYEAAAD ADVVFTSTAS ESLLFTKEHA EALPPISLAM GGVRLFVDIS
310 320 330 340 350 360
VPRNVGACLS QVEHARVYNV DDLKEVVEAN KEDRVRKAME AQAIITQELK RFEAWRDSLE
370 380 390 400 410 420
TVPTIKKLRS YADRIRASEL DKCLQKIGED NLNKKTRRSI EELSTGIVNK LLHGPLQHLR
430 440 450 460
CDGSDSRTLD ETLDNMHALN RMFNLDTEKA VLEQKIKAKV EKTQS