Q96328
Gene name |
SAC8 (G5, SAC1A, At3g51830, ATEM1.8) |
Protein name |
Phosphoinositide phosphatase SAC8 |
Names |
AtSAC8, Protein SUPPRESSOR OF ACTIN 1A, AtSAC1a, Protein SUPPRESSOR OF ACTIN 8, Putative transmembrane protein G5p, AtG5, SAC domain protein 8, SAC1-like protein AtSAC1a |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G51830 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q96328
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q96328-F1 | Predicted | AlphaFoldDB |
34 variants for Q96328
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_19220247_C_T | 4 | A>V | No | 1000Genomes | |
| ENSVATH12715338 | 39 | V>I | No | 1000Genomes | |
| ENSVATH06296891 | 44 | G>D | No | 1000Genomes | |
| ENSVATH00415120 | 52 | N>I | No | 1000Genomes | |
| ENSVATH06296895 | 54 | S>A | No | 1000Genomes | |
| tmp_3_19220552_G_T | 61 | V>F | No | 1000Genomes | |
| ENSVATH12715342 | 67 | V>L | No | 1000Genomes | |
| ENSVATH12715343 | 83 | T>M | No | 1000Genomes | |
| tmp_3_19220715_G_A | 85 | R>Q | No | 1000Genomes | |
| ENSVATH06296896 | 86 | E>G | No | 1000Genomes | |
| tmp_3_19220921_A_G | 120 | K>E | No | 1000Genomes | |
| ENSVATH14421386 | 128 | L>M | No | 1000Genomes | |
| ENSVATH06296904 | 186 | C>Y | No | 1000Genomes | |
| ENSVATH06296905 | 187 | K>R | No | 1000Genomes | |
| ENSVATH12715366 | 190 | G>S | No | 1000Genomes | |
| ENSVATH14421393 | 221 | C>S | No | 1000Genomes | |
| tmp_3_19221645_C_G | 225 | L>V | No | 1000Genomes | |
| tmp_3_19221776_A_G | 242 | N>S | No | 1000Genomes | |
| ENSVATH12715369 | 256 | K>N | No | 1000Genomes | |
| ENSVATH12715372 | 291 | P>S | No | 1000Genomes | |
| ENSVATH14421416 | 316 | Q>E | No | 1000Genomes | |
| ENSVATH06296918 | 337 | V>M | No | 1000Genomes | |
| ENSVATH02492148 | 361 | E>K | No | 1000Genomes | |
| ENSVATH14421420 | 365 | D>N | No | 1000Genomes | |
| ENSVATH12715397 | 370 | Q>H | No | 1000Genomes | |
| tmp_3_19223148_T_A | 375 | V>E | No | 1000Genomes | |
| ENSVATH12715401 | 427 | C>F | No | 1000Genomes | |
| ENSVATH12715401 | 427 | C>Y | No | 1000Genomes | |
| tmp_3_19224239_T_C | 471 | M>T | No | 1000Genomes | |
| tmp_3_19224247_G_A | 474 | A>T | No | 1000Genomes | |
| ENSVATH06296932 | 488 | N>S | No | 1000Genomes | |
| ENSVATH02492155 | 501 | L>V | No | 1000Genomes | |
| ENSVATH12715425 | 522 | Q>H | No | 1000Genomes | |
| ENSVATH06296939 | 534 | I>L | No | 1000Genomes |
No associated diseases with Q96328
1 regional properties for Q96328
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SAC domain | 65 - 455 | IPR002013 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphatidylinositol-4-phosphate phosphatase activity | Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphatidylinositol dephosphorylation | The process of removing one or more phosphate groups from a phosphatidylinositol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEIAPSTSRF | KLYDQFELLE | FPDKYVVKPI | ESPEEGFSVN | RRDGNIKPLD | ENASSGSPTR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSTIYGVGGT | IRLLAGTYLL | VITSREEVGN | FLGLPIFRVT | AMKFLPCNEA | LRFATAQEKK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DETYFRTLLQ | ALETTPGLYF | SYETDLTLNL | QRRCKLAEGW | NRKPMWKQAD | PRYVWNWHLL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EDLIECKLDG | FIIPILQGSY | QVAELKLKNS | PAVVSIMSRR | CTRRLGTRMW | RRGANLEGDA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANFVESEQIV | EINGFKFSLL | QVRGSIPLLW | EQIVDLSYKP | RLKINKHEET | PKVVQRHFHD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LCQRYGEIMA | VDLTDQHGDE | GALSKAYATE | MEKLPDVRYV | SFDFHQVCGT | TNFDNLGVLY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EQIGDEFEKQ | GYFLVDADEN | ILEEQKGVIR | SNCIDCLDRT | NVTQSFMGQK | SLNLQLQRIG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VCDSTECIST | FEDDYTKFRT | IWAEQGDEVS | LQYAGTYALK | GDLVRYGKQT | MTGAIKDGLS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AMSRYYLNNF | QDGVRQDALD | LISGRYTVGT | HSPSQLQPIG | SQPSFLPVAS | ALLIGGVTVT |
| 550 | 560 | 570 | 580 | ||
| SFTIHQAGRN | TQQYLASALW | AGVTAGVVAM | IKANGRHLTS | RPRLCHLI |