Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q96250

Entry ID Method Resolution Chain Position Source
AF-Q96250-F1 Predicted AlphaFoldDB

12 variants for Q96250

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_14021038_C_A 4 A>S No 1000Genomes
tmp_2_14021035_C_A 5 V>F No 1000Genomes
ENSVATH00257989 10 G>A No 1000Genomes
ENSVATH14580186 11 R>G No 1000Genomes
tmp_2_14020545_C_G 34 E>D No 1000Genomes
tmp_2_14020538_G_T 37 L>I No 1000Genomes
ENSVATH14580153 102 V>A No 1000Genomes
tmp_2_14019948_G_C 130 A>G No 1000Genomes
ENSVATH05647820 136 A>T No 1000Genomes
tmp_2_14019843_G_C 138 P>A No 1000Genomes
tmp_2_14019832_T_G 141 E>D No 1000Genomes
tmp_2_14019522_C_T 208 A>T No 1000Genomes

No associated diseases with Q96250

1 regional properties for Q96250

Type Name Position InterPro Accession
conserved_site ATP synthase, F1 complex, gamma subunit conserved site 307 - 320 IPR023632

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
  • Mitochondrion inner membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

9 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
mitochondrial proton-transporting ATP synthase complex A proton-transporting ATP synthase complex found in the mitochondrial membrane.
mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plant-type cell wall A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.

2 GO annotations of molecular function

Name Definition
proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
proton motive force-driven ATP synthesis The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAMAVFRREG RRLLPSIAAR PIAAIRSPLS SDQEEGLLGV RSISTQVVRN RMKSVKNIQK
70 80 90 100 110 120
ITKAMKMVAA SKLRAVQGRA ENSRGLWQPF TALLGDNPSI DVKKSVVVTL SSDKGLCGGI
130 140 150 160 170 180
NSTVVKVSRA LYKLNAGPEK EVQFVIVGEK AKAIMFRDSK NDIVLSVTEL NKNPLNYAQV
190 200 210 220 230 240
SVLADDILKN VEFDALRIVY NKFHSVVAFL PTVSTVLSPE IIEKESEIGG KLGELDSYEI
250 260 270 280 290 300
EGGETKGEIL QNLAEFQFSC VMFNAVLENA CSEMGARMSA MDSSSRNAGE MLDRLTLTYN
310 320
RTRQASITTE LIEIISGASA LEAAK