Q95SX7

PR
Gene name
RTase
Protein name
Probable RNA-directed DNA polymerase from transposon BS
Names
Reverse transcriptase
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
EC number
2.7.7.49: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

345-414 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q95SX7

Entry ID Method Resolution Chain Position Source
AF-Q95SX7-F1 Predicted AlphaFoldDB

No variants for Q95SX7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q95SX7

No associated diseases with Q95SX7

2 regional properties for Q95SX7

Type Name Position InterPro Accession
domain Reverse transcriptase domain 482 - 758 IPR000477
domain Endonuclease/exonuclease/phosphatase 105 - 217 IPR005135

Functions

Description
EC Number 2.7.7.49 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
RNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.

1 GO annotations of biological process

Name Definition
transposition, DNA-mediated Any process involved in a type of transpositional recombination which occurs via a DNA intermediate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNPLKILIWN ANGISRKAKD VELFAHNKKV DILLVTELRL KRGETVKIYG YAYYPAYRPS
70 80 90 100 110 120
LNNNSVGGVA VFVRTTLRHF PQRVIETRHI QLSSVKVATG LGDLQFSAIY CSPSTRIEER
130 140 150 160 170 180
HFTDIIRACG QRYLVGGDWN ARHWLWGDTC NSPRGRELAE ALSVTGAKIL ATGSPTRYPY
190 200 210 220 230 240
VPSHTPSCID FAVYHGIPDH LATITQSWDL DSDHLPLIIS IETDSTHVNP SPRLVTKHTD
250 260 270 280 290 300
LLAFSRQLES LISLNTTLNS GEEIEMAVDN LTESIHRAAA VSTSPVPRIG TTYGIVLTRE
310 320 330 340 350 360
ARELLTQKRR LRRRAIRSQD PWDRLLWNRA AKQLRNVLRE LRSNFFEQKL ASMDYTVDAG
370 380 390 400 410 420
YSLWKCTKSL KRQPFRQVPI RCPGGELAKN EEEQANCFAN HLETRFTHFQ FATTEQYQET
430 440 450 460 470 480
LDSLETPLQM SLPIKPIRVE EIVEAIKSLP LKKSPGIDNV CNATLKALPV RAILYLALIY
490 500 510 520 530 540
NAILRVQFFP KQWKMAAILM IHKPGKPEES PESYRPISLL SSLSKLWERL IANRLNDIMT
550 560 570 580 590 600
ERRILPDHQF GFRQGHSTVE QVHRLTKHIL QAFDDKEYCN AVFIDMQQAF DRVWHDGLIS
610 620 630 640 650 660
KVKKLFPAPY YGVLKSYLED RRFMVRVRNS YSIPRVMRAG VPQGSVLGPL LYSVFTADLP
670 680 690 700 710 720
CPNAYHMADP RKALLATYAD DIALLYSSNC CNEAARGLQE YLTTLAAWCK RWILKVNPQK
730 740 750 760 770 780
TINPCFTLKT LSPVTAPIEL EGVILDQPSQ AKYLGITLDK RLTFGPHLKA TTRRCYQRMQ
790 800 810 820 830 840
QLRWLLNRKS TMTLRAKRAV YVHCVAPIWL YGIQIWGIAA KSNYNRIQVL QNRAMRAITD
850 860 870 880 890 900
CPYYVRGTTL HRDLNLHTVE EQISRHTSRY SDRLRRHHSI LARRLLPARP LRRLKRKGFA
KTLGQP