Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q95NC7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q95NC7-F1 | Predicted | AlphaFoldDB |
No variants for Q95NC7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q95NC7 | |||||
No associated diseases with Q95NC7
1 regional properties for Q95NC7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 47 - 297 | IPR017452 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| external side of plasma membrane | The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| C-C chemokine receptor activity | Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| chemotaxis | The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). |
| immune response | Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. |
| inflammatory response | The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDYQVSSPTY | DIDYYTSEPC | QKVNVKQIAA | RLLPPLYSLV | FIFGFVGNIL | VVLILINCKR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LKSMTDIYLL | NLAISDLFFL | LTVPFWAHYA | AARWDFGNTM | CQLLTGLYFI | GFFSGIFFII |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLTIDRYLAI | VHAVFALKAR | TVTFGVVTSV | ITWVVAVFAS | LPGIIFTRSQ | REGLHYTCSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HFPYSQYQFW | KNFQTLKIVI | LGLVLPLLVM | VICYSGILKT | LLRCRNEKKR | HRAVRLIFTI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MIVYFLFWAP | YNIVLLLNTF | QEFFGLNNCS | SSNRLDQAMQ | VTETLGMTHC | CINPIIYAFV |
| 310 | 320 | 330 | 340 | 350 | |
| GEKFRNYLLV | FFQKHIAKRF | CKCCSIFQQE | APERASSVYT | RSTGEQEISV | GL |