Q95L87

PR
Gene name
NR5A1 (SF1)
Protein name
Steroidogenic factor 1
Names
SF-1, STF-1, Nuclear receptor subfamily 5 group A member 1
Species
Notamacropus eugenii (Tammar wallaby) (Macropus eugenii)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

55-282 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q95L87

Entry ID Method Resolution Chain Position Source
AF-Q95L87-F1 Predicted AlphaFoldDB

No variants for Q95L87

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q95L87

No associated diseases with Q95L87

2 regional properties for Q95L87

Type Name Position InterPro Accession
domain Nuclear hormone receptor, ligand-binding domain 224 - 461 IPR000536
domain Zinc finger, nuclear hormone receptor-type 10 - 85 IPR001628

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.
nuclear receptor activity A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytoplasm, which leads to its tranlocation to the nucleus.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
zinc ion binding Binding to a zinc ion (Zn).

4 GO annotations of biological process

Name Definition
female gonad development The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
male gonad development The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
positive regulation of gene expression Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
sex determination Any process that establishes and transmits the specification of sexual status of an individual organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDYSYDEDLD ELCPVCGDKV SGYHYGLLTC ESCKGFFKRT VQNNKHYTCT ESQNCKIDKT
70 80 90 100 110 120
QRKRCPYCRF QKCLTVGMRL EAVRADRMRG GRNKFGPMYK RDRALKQQKK ALIRANGFKL
130 140 150 160 170 180
ETGPSMGPPP QTDYPLAPAL HPGAKGLAPA PPAGPPGDYE RGPYGPPGVP MAVPTHGPLA
190 200 210 220 230 240
GYLYPAFPGR AIKSEYPEPY ASPHEPAPPY GYPEPYPSGP GLPGVPELIL KLLQLEPDEG
250 260 270 280 290 300
QLKARILACL QEPSKGRPDR PTPFGLMCKM ADQTLFSIVE WARSCVVFKE LEVADQMKLL
310 320 330 340 350 360
QNCWSELLVF DHIYRQIQHG KEGSILLVTG QEVDLSTVAA QAGSLLHSLV LRAQDLVQQL
370 380 390 400 410 420
HSLQVDRQEF VCLKFLILFS LDVKFLENHG LAKDAQEKAN SALLEYTMCH YPHCGDKFRQ
430 440 450 460
LLLRLAEVRS LSMQAEEYLY HKHLGGEVPC NNLLIEMLHA KRT