Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q95KC3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q95KC3-F1 | Predicted | AlphaFoldDB |
No variants for Q95KC3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q95KC3 | |||||
No associated diseases with Q95KC3
1 regional properties for Q95KC3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 42 - 298 | IPR017452 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| intrinsic component of membrane | The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled ADP receptor activity | Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP). |
| platelet aggregation | The adhesion of one platelet to one or more other platelets via adhesion molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQAIDNLTSA | PGNTSLCTRD | YKITQVLFPL | LYTVLFFVGL | ITNSLAMRIF | FQIRSKSNFI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IFLKNTVISD | LLMILTFPFK | ILSDAKLGAG | PLRTFVCQVT | SVIFYFTMYI | SISFLGLITI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DRYQKTTRPF | KTSNPKNLLG | AKILSVLIWA | FMFLLSLPNM | ILTNRRPRDK | NVKKCSFLKS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EFGLVWHEIV | NYICQVIFWI | NFLIVIVCYT | LITKELYRSY | VRTRGVGKVP | RKKVNVKVFI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IIAVFFICFV | PFHFARIPYT | LSQTRDVFDC | AAENTLFYVK | ESTLWLTSLN | ACLDPFIYFF |
| 310 | 320 | 330 | 340 | ||
| LCKSFRNSLI | SMLKCPNSAT | SQSQDNRKKE | QDGGDPNEET | PM |