Q95216
Gene name |
HLTF (RUSH1, SMARCA3) |
Protein name |
Helicase-like transcription factor |
Names |
RING-type E3 ubiquitin transferase HLTF, RUSH-1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3, Sucrose nonfermenting protein 2-like 3 |
Species |
Oryctolagus cuniculus (Rabbit) |
KEGG Pathway |
ocu:100009232 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q95216
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q95216-F1 | Predicted | AlphaFoldDB |
No variants for Q95216
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q95216 | |||||
No associated diseases with Q95216
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
7 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent chromatin remodeler activity | An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. |
| transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSWMFKRDPV | WKYLQTVQYG | VHGNFSRLSY | PTFFPRFEFQ | DIIPPDDFLT | SDEELDSVLF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GTLRGHVVGL | RYYTGVVNNN | EMVALQREPN | NPYDKNAIKV | NNVNGNQVGY | LKKELAAALA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YIMDNKLAQI | EGVVPYGANN | AFTMPLQMTF | WGKEENRKAV | LDQLKKHGFK | LGPAPKTLGF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SLESGWGSGR | AGPSYSMPVH | AAIQMTTEQL | KTEFDKLFED | LKEDDKTQEM | EPAEAVETPL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LPHQKQALAW | MVSRENSREL | PPFWELRNDL | YYNTITNFSE | KDQPENVHGG | ILADDMGLGK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TLTAIAVILT | NFHDGKPLPV | ERMKKNQVKK | ECNSSESDKP | GRKDTIKKTD | GLSKEGSRYS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EEPSISDVKK | NKYSMSELSS | SQPKRKKIAV | QYIESSDSEE | IEISELPQKM | KGKLKNVQSE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TKRVKVGPSK | IKEDTAFACA | LTSSASTTTK | KILKKGASAQ | RVQRKLMFEE | RPRTTLIICP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LSVLSNWIDQ | FGQHIKSDVH | LNFYVYYGPD | RIRDPALLSK | QDIVLTTYNI | LTHDYGTKGD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SPLHSIRWLR | VILDEGHAIR | NPNAQQTKAV | LDLEAERRWV | LTGTPIQNSL | KDLWSLLSFL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KLKPFVDREW | WHRTIQRPVT | MGDEGGLRRL | QSLIKNITLR | RTKTSKIKGK | PVLELPERPV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FIQHITLSDE | ERKIYQSVKS | EGKATIGRYF | NEGTVLAHYA | DVLGLLLRLR | QICCHTHLLT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NTVSSSGPSG | NDTPEELRKK | LIKKMKLILS | SGSDEECAIC | LDSLTVPVIT | HCAHVFCKPC |
| 790 | 800 | 810 | 820 | 830 | 840 |
| ICQCIQNEQP | HAKCPLCRND | IHGDNLLECP | PEELACDSEK | KSNMEWTSSS | KINALMHALI |
| 850 | 860 | 870 | 880 | 890 | 900 |
| DLRTKNPNIK | SLVVSQFTTF | LSLIETPLKA | SGFVFTRLDG | SMAQKKRVES | IQCFQNTEAG |
| 910 | 920 | 930 | 940 | 950 | 960 |
| SPTIMLLSLK | AGGVGLNLCA | ASRVFLMDPA | WNPAAEDQRF | DRCHRLGQKQ | EVIITKFIVK |
| 970 | 980 | 990 | 1000 | ||
| DSVEENMLKI | QNTKRELAAG | AFGTKKNANE | MKQAKINEIR | TLIDL |