Q94E49

PR
Gene name
PID2 (Os01g0174700, LOC_Os01g07940, OSJNBa0089K24.26)
Protein name
Protein kinase PINOID 2
Names
Protein PID-like, OsPIDlike
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4327129
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

233-243 (Activation loop from InterPro)

Target domain

80-443 (Protein kinase domain)

Relief mechanism

Assay

332-340 (Activation loop from InterPro)

Target domain

80-443 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q94E49

Entry ID Method Resolution Chain Position Source
AF-Q94E49-F1 Predicted AlphaFoldDB

No variants for Q94E49

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q94E49

No associated diseases with Q94E49

5 regional properties for Q94E49

Type Name Position InterPro Accession
domain Protein kinase domain 17 - 269 IPR000719
domain Kinase associated domain 1 (KA1) 459 - 507 IPR001772
active_site Serine/threonine-protein kinase, active site 136 - 148 IPR008271
domain Ubiquitin-associated domain 290 - 330 IPR015940
binding_site Protein kinase, ATP binding site 23 - 46 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

3 GO annotations of biological process

Name Definition
auxin-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
cotyledon development The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
protein phosphorylation The process of introducing a phosphate group on to a protein.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q0DCT8 Os06g0291600 Protein kinase G11A Oryza sativa subsp japonica (Rice) PR
O64682 PID Protein kinase PINOID Arabidopsis thaliana (Mouse-ear cress) PR
Q9LUL2 WAG2 Serine/threonine-protein kinase WAG2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SUA3 D6PKL1 Serine/threonine-protein kinase D6PKL1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAAIKEESDY DSSRSSLTAP DSRRSWISDI GSSSSVSARS FGGDTPASSC RYKPHKANQA
70 80 90 100 110 120
EWEAIRRLRA GAGRVGLEHF RLVRRLGSGD LGNVYLCRLR EPWSSSSMTT TAGGCLYAMK
130 140 150 160 170 180
VVDKDALAFR KKLRRAEVER DILRTLDHPF LPTLYADFEA SHYACLVMEF CPGGDLHVAR
190 200 210 220 230 240
QRQPGRRFTV SSTRFYVAET VLALEYLHMM GVVYRDLKPE NVLVRGDGHI MLSDFDLSLK
250 260 270 280 290 300
CDVVPKLLRP ARSAAAGGKP PLPPPSSCVP PTIQPVLSCI FRGVHKCHHA KECAGGGAAA
310 320 330 340 350 360
GNNGDGDGND EEAETETAEP EVVVVEPVAA RSKSFVGTHE YLAPEVISGQ GHGSAVDWWT
370 380 390 400 410 420
LGVFMYEMLY GRTPFKGESN EKTLINIIKQ PVTFPRLAGA AAAGEWEEMK TAQDLMLQLL
430 440 450 460 470 480
AKNPKKRLGS TMGSAEVKRH PFFKGVNWAL VRSVRPPEVP APPAPAPKKV MTMSKKERQE
490
PYNYRPENHF DYF