Q94CE4

PR
Gene name
BCA4
Protein name
Beta carbonic anhydrase 4
Names
AtbCA4, AtbetaCA4, Beta carbonate dehydratase 4
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G70410
EC number
4.2.1.1: Hydro-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-102 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q94CE4

Entry ID Method Resolution Chain Position Source
AF-Q94CE4-F1 Predicted AlphaFoldDB

16 variants for Q94CE4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01515486 14 A>T No 1000Genomes
tmp_1_26536507_T_C 22 E>G No 1000Genomes
tmp_1_26536462_T_G 37 D>A No 1000Genomes
ENSVATH05119488 62 E>G No 1000Genomes
tmp_1_26536115_G_T 63 L>I No 1000Genomes
ENSVATH14462485 64 D>E No 1000Genomes
tmp_1_26536086_T_A 72 E>D No 1000Genomes
ENSVATH05119485 72 E>G No 1000Genomes
ENSVATH05119484 79 T>A No 1000Genomes
ENSVATH13784740 84 E>D No 1000Genomes
ENSVATH05119476 92 L>S No 1000Genomes
ENSVATH13784725 121 N>D No 1000Genomes
ENSVATH13784724 136 M>L No 1000Genomes
ENSVATH00135706 152 V>I No 1000Genomes
ENSVATH13784711 185 A>D No 1000Genomes
ENSVATH05119444 263 T>S No 1000Genomes

No associated diseases with Q94CE4

2 regional properties for Q94CE4

Type Name Position InterPro Accession
conserved_site Carbonic anhydrase, prokaryotic-like, conserved site 109 - 116 IPR015892-1
conserved_site Carbonic anhydrase, prokaryotic-like, conserved site 153 - 173 IPR015892-2

Functions

Description
EC Number 4.2.1.1 Hydro-lyases
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chloroplast envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
carbonate dehydratase activity Catalysis of the reaction: H2CO3 = CO2 + H2O.
zinc ion binding Binding to a zinc ion (Zn).

4 GO annotations of biological process

Name Definition
carbon utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
negative regulation of stomatal complex development Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development.
regulation of stomatal movement Any process that modulates the frequency, rate or extent of stomatal movement.
response to carbon dioxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9ZUC2 BCA3 Beta carbonic anhydrase 3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAPAFGKCFM FCCAKTSPEK DEMATESYEA AIKGLNDLLS TKADLGNVAA AKIKALTAEL
70 80 90 100 110 120
KELDSSNSDA IERIKTGFTQ FKTEKYLKNS TLFNHLAKTQ TPKFLVFACS DSRVCPSHIL
130 140 150 160 170 180
NFQPGEAFVV RNIANMVPPF DQKRHSGVGA AVEYAVVHLK VENILVIGHS CCGGIKGLMS
190 200 210 220 230 240
IEDDAAPTQS DFIENWVKIG ASARNKIKEE HKDLSYDDQC NKCEKEAVNV SLGNLLSYPF
250 260 270
VRAEVVKNTL AIRGGHYNFV KGTFDLWELD FKTTPAFAFS