Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

3 structures for Q949P3

Entry ID Method Resolution Chain Position Source
1XFI X-ray 170 A A 2-367 PDB
2Q40 X-ray 170 A A 2-367 PDB
AF-Q949P3-F1 Predicted AlphaFoldDB

27 variants for Q949P3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_7544080_C_T 4 D>N No 1000Genomes
tmp_2_7543977_G_A 38 A>V No 1000Genomes
tmp_2_7543954_T_C 46 I>V No 1000Genomes
tmp_2_7543937_A_C 51 N>K No 1000Genomes
tmp_2_7543929_G_A 54 P>L No 1000Genomes
ENSVATH00234488 64 I>T No 1000Genomes
ENSVATH05513481 67 P>T No 1000Genomes
ENSVATH01826863 75 K>N No 1000Genomes
ENSVATH00234484 86 D>N No 1000Genomes
tmp_2_7543286_T_C 92 E>G No 1000Genomes
ENSVATH01826835 137 Q>E No 1000Genomes
ENSVATH01826834 140 S>N No 1000Genomes
ENSVATH05513475 167 L>H No 1000Genomes
tmp_2_7542890_C_T 168 G>D No 1000Genomes
tmp_2_7542778_T_C 178 R>G No 1000Genomes
tmp_2_7542756_G_C 185 A>G No 1000Genomes
tmp_2_7542680_C_G 210 K>N No 1000Genomes
ENSVATH05513472 211 S>P No 1000Genomes
ENSVATH13235039 237 L>S No 1000Genomes
ENSVATH05513468 240 R>Q No 1000Genomes
ENSVATH00234473 242 A>T No 1000Genomes
tmp_2_7542344_T_G 257 I>L No 1000Genomes
ENSVATH00234470 259 C>Y No 1000Genomes
ENSVATH00234469 271 D>N No 1000Genomes
ENSVATH13234973 306 A>V No 1000Genomes
ENSVATH13234972 316 I>V No 1000Genomes
ENSVATH05513459 324 I>T No 1000Genomes

No associated diseases with Q949P3

No regional properties for Q949P3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q949P3

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
metal ion binding Binding to a metal ion.
pantothenate kinase activity Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.

1 GO annotations of biological process

Name Definition
coenzyme A biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MESDSEMVPF PQLPMPIENN YRACTIPYRF PSDDPKKATP NEISWINVFA NSIPSFKKRA
70 80 90 100 110 120
ESDITVPDAP ARAEKFAERY AGILEDLKKD PESHGGPPDG ILLCRLREQV LRELGFRDIF
130 140 150 160 170 180
KKVKDEENAK AISLFPQVVS LSDAIEDDGK RLENLVRGIF AGNIFDLGSA QLAEVFSRDG
190 200 210 220 230 240
MSFLASCQNL VPRPWVIDDL ENFQAKWINK SWKKAVIFVD NSGADIILGI LPFARELLRR
250 260 270 280 290 300
GAQVVLAANE LPSINDITCT ELTEILSQLK DENGQLLGVD TSKLLIANSG NDLPVIDLSR
310 320 330 340 350 360
VSQELAYLSS DADLVIVEGM GRGIETNLYA QFKCDSLKIG MVKHLEVAEF LGGRLYDCVF
KFNEVQS