Q93MW7

PR
Gene name
Protein name
Lipase
Names
Diheptanoyl glycerophosphocholine esterase, Extracellular lipase, GDSL-like lipase, Palmitoyl-CoA hydrolase, SRL
Species
Streptomyces rimosus
KEGG Pathway
EC number
3.1.1.3: Carboxylic ester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-55 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q93MW7

Entry ID Method Resolution Chain Position Source
5MAL X-ray 171 A A/B 35-268 PDB
AF-Q93MW7-F1 Predicted AlphaFoldDB

No variants for Q93MW7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q93MW7

No associated diseases with Q93MW7

1 regional properties for Q93MW7

Type Name Position InterPro Accession
domain SGNH hydrolase-type esterase domain 40 - 256 IPR013830

Functions

Description
EC Number 3.1.1.3 Carboxylic ester hydrolases
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

5 GO annotations of molecular function

Name Definition
carboxylic ester hydrolase activity Catalysis of the hydrolysis of a carboxylic ester bond.
myristoyl-CoA hydrolase activity Catalysis of the reaction: myristoyl-CoA + H2O <=> H+ + tetradecanoate + coenzyme A.
palmitoyl-CoA hydrolase activity Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
phospholipase activity Catalysis of the hydrolysis of a glycerophospholipid.
triglyceride lipase activity Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.

1 GO annotations of biological process

Name Definition
lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLSRRAATA SALLLTPALA LFGASAAVSA PRIQATDYVA LGDSYSSGVG AGSYDSSSGS
70 80 90 100 110 120
CKRSTKSYPA LWAASHTGTR FNFTACSGAR TGDVLAKQLT PVNSGTDLVS ITIGGNDAGF
130 140 150 160 170 180
ADTMTTCNLQ GESACLARIA KARAYIQQTL PAQLDQVYDA IDSRAPAAQV VVLGYPRFYK
190 200 210 220 230 240
LGGSCAVGLS EKSRAAINAA ADDINAVTAK RAADHGFAFG DVNTTFAGHE LCSGAPWLHS
250 260
VTLPVENSYH PTANGQSKGY LPVLNSAT