Q92QH6

PR
Gene name
rpoC
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
KEGG Pathway
sme:SMc01316
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1340-1401 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q92QH6

Entry ID Method Resolution Chain Position Source
AF-Q92QH6-F1 Predicted AlphaFoldDB

No variants for Q92QH6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q92QH6

No associated diseases with Q92QH6

6 regional properties for Q92QH6

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 346 - 487 IPR000722
domain RNA polymerase, N-terminal 237 - 516 IPR006592
domain RNA polymerase Rpb1, domain 3 491 - 644 IPR007066
domain RNA polymerase Rpb1, domain 1 16 - 344 IPR007080
domain RNA polymerase Rpb1, domain 5 762 - 1309 IPR007081
domain RNA polymerase Rpb1, domain 4 673 - 759 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNQEVMNLFN PQVPAQTFDS IRISIASPEK ILSWSYGEIK KPETINYRTF KPERDGLFCA
70 80 90 100 110 120
RIFGPIKDYE CLCGKYKRMK YKGIICEKCG VEVTLSRVRR ERMGHIELAA PVAHIWFLKS
130 140 150 160 170 180
LPSRIATLLD MTLKDIERVL YFENYIVTEP GLTSLKENQL LSEEEYMIAV DEFGEDQFTA
190 200 210 220 230 240
MIGAEAIYEM LASMNLEKIA GDLRSEMAET TSDLKQKKLM KRLKIVENFM ESGNRPEWMI
250 260 270 280 290 300
MKVVPVIPPD LRPLVPLDGG RFATSDLNDL YRRVINRNNR LKRLIELRAP GIIIRNEKRM
310 320 330 340 350 360
LQESVDALFD NGRRGRVITG ANKRPLKSLS DMLKGKQGRF RQNLLGKRVD YSGRSVIVTG
370 380 390 400 410 420
PELKLHQCGL PKKMALELFK PFIYARLDAK GYSSTVKQAK KLVEKEKPEV WDILDEVIRE
430 440 450 460 470 480
HPVLLNRAPT LHRLGIQAFE PILVEGKAIQ LHPLVCTAFN ADFDGDQMAV HVPLSLEAQL
490 500 510 520 530 540
EARVLMMSTN NILHPANGAP IIVPSQDMVL GLYYLSIMNQ NEPGEGMAFS DMGELHHALE
550 560 570 580 590 600
TKAVTLHAKI RGRYKTVDAE GNPVSKIYET TPGRMIIGEL LPKNPNVPFE TCNQEMTKKN
610 620 630 640 650 660
ISKMIDTVYR HCGQKDTVIF CDRIMQLGFS HACRAGISFG KDDMVIPDTK VKIVGDTEAL
670 680 690 700 710 720
VKEYEQQYND GLITQGEKYN KVVDAWGKAT EKVAEEMMAR IKAVEFDDSG RQKPMNSIYM
730 740 750 760 770 780
MSHSGARGSP NQMRQLGGMR GLMAKPSGEI IETPIISNFK EGLTVNEYFN STHGARKGLA
790 800 810 820 830 840
DTALKTANSG YLTRRLVDVA QDCIVTHTDC GTDKGLTMTA IVDAGQVVAS IGQRILGRTA
850 860 870 880 890 900
LDNIDNPVTG ERIVDAGKMI LEPDVVAIEK AGIQSVRIRS ALTCEIQTGV CGVCYGRDLA
910 920 930 940 950 960
RGTPVNMGEA VGVIAAQSIG EPGTQLTMRT FHLGGTATVV DQSFLEASYE GTVQIKNRNM
970 980 990 1000 1010 1020
LRNSDGVLVA MGRNMAIQIL DERGVERSSQ RVAYGSKIFV DDGDKVKRGQ RFAEWDPYTR
1030 1040 1050 1060 1070 1080
PMMTEVEGTV HFEDVVDGIS VLESTDESTG ITKRQVIDWR STPRGTDLKP AIVIKDKNGN
1090 1100 1110 1120 1130 1140
IAKLARGGEA RFMLSVDAIL SVEPGQKVSQ GDVLARSPLE SAKTKDITGG LPRVAELFEA
1150 1160 1170 1180 1190 1200
RRPKDHAIIA EIDGTIRFGR DYKNKRRVMI EPAEDGVEPV EYLIPKGKPF HLQDGDYIEK
1210 1220 1230 1240 1250 1260
GDYILDGNPA PHDILAIKGV EALASYLVNE IQEVYRLQGV VINDKHIEVI VRQMLQKVEI
1270 1280 1290 1300 1310 1320
TDAGDSTYIV GDNVDRIELE DVNDSLLAEG KKPAFGEPVL LGITKASLQT PSFISAASFQ
1330 1340 1350 1360 1370 1380
ETTKVLTEAA VAGKTDNLQG LKENVIVGRL IPAGTGGTMT QIRRIATARD ELILEERRKG
1390 1400
TGAESATPML ADMANDPAAA E