Q92MK7

PR
Gene name
clpB (R02608, SMc02433)
Protein name
Chaperone protein ClpB
Names
Species
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
KEGG Pathway
sme:SMc02433
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

104-188 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q92MK7

Entry ID Method Resolution Chain Position Source
AF-Q92MK7-F1 Predicted AlphaFoldDB

No variants for Q92MK7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q92MK7

No associated diseases with Q92MK7

9 regional properties for Q92MK7

Type Name Position InterPro Accession
domain AAA+ ATPase domain 199 - 345 IPR003593-1
domain AAA+ ATPase domain 599 - 750 IPR003593-2
domain ATPase, AAA-type, core 204 - 317 IPR003959-1
domain ATPase, AAA-type, core 598 - 762 IPR003959-2
domain Clp, repeat (R) domain 3 - 147 IPR004176
conserved_site ClpA/B, conserved site 1 295 - 307 IPR018368
domain Clp ATPase, C-terminal 768 - 857 IPR019489
conserved_site ClpA/B, conserved site 2 633 - 651 IPR028299
domain ClpA/ClpB, AAA lid domain 343 - 445 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIEKYSERV RGFLQSAQTY ALAEGHQQFT PEHVLKVLLD DDQGMAASLI ERAGGNAREA
70 80 90 100 110 120
KVGTAAALAK LPKVTGGNGS VYLSQPLAKV FTAAEDAAKK AGDSFVTVER LLLALAIESS
130 140 150 160 170 180
AATASILSKA GVTPTKLNQV INEIRKGRTA DSANAEQGFD SLKKYARDLT AEAREGKLDP
190 200 210 220 230 240
VIGRDDEIRR TIQVLSRRTK NNPVLIGEPG VGKTAIAEGL ALRIVNGDVP ESLKDKRLMA
250 260 270 280 290 300
LDMGALIAGA KFRGEFEERL KAVLNEVRSE GGEIILFIDE MHTLVGAGKA DGAMDASNLL
310 320 330 340 350 360
KPALARGELH CVGATTLDEY RKHVEKDAAL ARRFQPVMVE EPTVEDTISI LRGLKEKYEQ
370 380 390 400 410 420
HHKVRISDSA LVAAAALSNR YITDRFLPDK AIDLMDEAAS RLRMQVDSKP EELDELDRRV
430 440 450 460 470 480
IQLKIEREAL KKETDVSSKD RLAKLELDLS SLEEEAAALT ARWQAEKQKL GQAADLKKQL
490 500 510 520 530 540
DEARNELQIA QRKGEFQRAG ELAYGVIPNL EKELAEAESQ DGASANPMVQ EVVTPDNIAH
550 560 570 580 590 600
IVSRWTGIPV DKMLEGERDK LLRMEDELAK WVVGQGDAVQ AVSRAVRRSR AGLQDPNRPI
610 620 630 640 650 660
GSFIFLGPTG VGKTELTKAL ARFLFDDETA LMRIDMSEYM EKHSVARLIG APPGYVGYEE
670 680 690 700 710 720
GGALTESVRR RPYQVVLFDE IEKAHPDVFN VLLQVLDDGR LTDGQGRTVD FKNTMIIMTS
730 740 750 760 770 780
NLGAEYLTAL GENEDSDAVR DQVMEVVRAA FRPEFLNRVD EIILFHRLRR SEMGAIVDIQ
790 800 810 820 830 840
LERLRKLLSD RKITLELEDD ARVFLADRGY DPAYGARPLK RAIQKYVQDP LAEKVLQGEF
850 860
PDGSVIKVVA GSDRLNFKRG AGANKEAA