Q92A32
Gene name |
ilvD |
Protein name |
Dihydroxy-acid dehydratase |
Names |
DAD |
Species |
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) |
KEGG Pathway |
lin:ilvD |
EC number |
4.2.1.9: Hydro-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q92A32
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q92A32-F1 | Predicted | AlphaFoldDB |
No variants for Q92A32
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q92A32 | |||||
No associated diseases with Q92A32
2 regional properties for Q92A32
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site | 121 - 131 | IPR020558-1 |
| conserved_site | Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site | 465 - 476 | IPR020558-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.1.9 | Hydro-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2 iron, 2 sulfur cluster binding | Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| dihydroxy-acid dehydratase activity | Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| isoleucine biosynthetic process | The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. |
| valine biosynthetic process | The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRSDKIKKGV | EQAPARSLLH | ATGQIKSPGD | MDKPFIAICN | SYIDIVPGHV | HLRELADVAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EAIREAGGIP | FEFNTIGVDD | GIAMGHIGMR | YSLPSREVIA | DAAETVINAH | WFDGVFYIPN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CDKITPGMLL | ASVRTNVPAI | FCSGGPMKAG | LSAHGKALTL | SSVFEAVGAF | KEGSMSQEDF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LDMEANACPT | CGSCAGMFTA | NSMNCLMEIL | GMAVPGNGTT | LAVSDARREL | IRESAFHLMD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LVKKDIRPRD | IITKDAIDDA | FALDMAMGGS | TNTVLHTLAL | ANEAGIEDYD | LERINDIAKR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VPYLSKIAPS | SSYSMHDVHE | AGGVSAIIKE | LVDLGGAIHP | DRITVTGKTI | RENVADAKIN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NTDVIHPKEN | PYSPVGGLSM | LFGNIAPKGA | TIKVGGVDPS | VQVFKGEAIC | FSSHDEAVEA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IDNHTVREGH | VVVIRYEGPK | GGPGMPEMLA | PTSSIVGRGL | GKDVALITDG | RFSGATRGIA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VGHISPEAAA | GGPIALVHDG | DIITIDLPNR | TLNVDVPDEV | LEERRKELPK | FKAKVKTGYL |
| 550 | 560 | ||||
| ARYTALVTSA | HTGGILQIPE | DLID |