Q928R9
Gene name |
gadB (lin2463) |
Protein name |
Glutamate decarboxylase beta |
Names |
GAD-beta |
Species |
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) |
KEGG Pathway |
lin:lin2463 |
EC number |
4.1.1.15: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q928R9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q928R9-F1 | Predicted | AlphaFoldDB |
No variants for Q928R9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q928R9 | |||||
No associated diseases with Q928R9
15 regional properties for Q928R9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Immunodeficiency lentiviral matrix, N-terminal | 2 - 127 | IPR000071 |
| domain | Reverse transcriptase domain | 631 - 821 | IPR000477 |
| domain | Integrase, C-terminal, retroviral | 1370 - 1417 | IPR001037 |
| domain | Integrase, catalytic core | 1201 - 1351 | IPR001584 |
| domain | Zinc finger, CCHC-type | 392 - 408 | IPR001878-1 |
| domain | Zinc finger, CCHC-type | 413 - 429 | IPR001878-2 |
| active_site | Aspartic peptidase, active site | 510 - 521 | IPR001969 |
| domain | Peptidase A2A, retrovirus, catalytic | 508 - 577 | IPR001995 |
| domain | Ribonuclease H domain | 1021 - 1144 | IPR002156 |
| domain | Integrase, N-terminal zinc-binding domain | 1150 - 1191 | IPR003308 |
| domain | Reverse transcriptase connection | 905 - 1006 | IPR010659 |
| domain | Reverse transcriptase thumb | 829 - 890 | IPR010661 |
| domain | Retropepsins | 494 - 585 | IPR018061 |
| domain | Retropepsin-like catalytic domain | 499 - 579 | IPR034170 |
| domain | Retroviral nucleocapsid Gag protein p24, C-terminal domain | 277 - 349 | IPR045345 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.15 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutamate decarboxylase activity | Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glutamate metabolic process | The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLYSKENKES | YLEPVFGSSA | EDRDIPKYTL | AKEPLEPRIA | YRLVKDELLD | EGSARQNLAT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FCQTYMEDEA | TKLMSETLEK | NAIDKSEYPR | TAELENRCVN | IIADLWHAPK | DQKFMGTSTI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GSSEACMLGG | MAMKFAWRKR | AEKLGLDIYA | QKPNLVISSG | YQVCWEKFCV | YWDIDMRVVP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MDKDHMQLNT | DQVLDYVDEY | TIGVVGILGI | TYTGRYDDIY | ALNEKLEEYN | SKTDYKVYIH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VDAASGGFFT | PFVEPDIIWD | FRLKNVISIN | TSGHKYGLVY | PGIGWVLWKD | ESYLPEELIF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KVSYLGGEMP | TMQINFSRSA | SHIIGQYYNF | LRYGFEGYRT | IHQKTSDVAQ | YLAHAVEQTG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YFDIYNDGSH | LPIVCYKLKD | DANVKWTLYD | LADRLQMRGW | QVPAYPLPKN | LENIIIQRYV |
| 430 | 440 | 450 | 460 | ||
| CRADLGFNMA | EEFIQDFQAS | IQELNNAHIL | FHDTQQSGVH | GFTH |