Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q92361

Entry ID Method Resolution Chain Position Source
AF-Q92361-F1 Predicted AlphaFoldDB

5 variants for Q92361

Variant ID(s) Position Change Description Diseaes Association Provenance
I_3279524_C_T 92 V>I No Jeffares_SNPs
I_3279315_A_G 144 M>T No Jeffares_SNPs
I_3279303_T_A 148 E>V No Jeffares_SNPs
I_3279279_G_A 156 S>F No Jeffares_SNPs
I_3279258_A_G 163 M>T No Jeffares_SNPs

1 associated diseases with Q92361

Without disease ID

No regional properties for Q92361

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q92361

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
DNA ligase IV complex A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
double-strand break repair via nonhomologous end joining The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
meiotic cell cycle Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKFFLSLKDF KGEKFVLRSE LDESSAFLCA ISPTCRYVLR DEIPWKRLQR NVTSESLTDE
70 80 90 100 110 120
LIVDLLCGRS ESKHTLQLVV LENLCRIYIN YVDPFPLRIA WFELEQQALK DHEHFDVLWE
130 140 150 160 170 180
CSHSIKDLAL ASMAQQKNEL QKLMAYTEQL QEECKSRERK LIMKFADMIK NARNNEDNED
190 200 210 220 230 240
NHHINYEDES DVGTDEQKQQ EGVNSSAVSD TDESAVSDEF MQIKEEFPMK ALSASPTADA
250 260
SPESAGEDDS HRRSSHESSE TVSE