Q92036

PR
Gene name
ATP12A
Protein name
Potassium-transporting ATPase alpha chain 2
Names
Non-gastric H(+)/K(+) ATPase subunit alpha, Proton pump
Species
Rhinella marina (Cane toad) (Bufo marinus)
KEGG Pathway
EC number
7.2.2.19: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-93 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q92036

Entry ID Method Resolution Chain Position Source
AF-Q92036-F1 Predicted AlphaFoldDB

No variants for Q92036

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q92036

No associated diseases with Q92036

No regional properties for Q92036

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q92036

Functions

Description
EC Number 7.2.2.19 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
metal ion binding Binding to a metal ion.
P-type potassium:proton transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGTEANSDVY STAINGINEI GYPDKEKEED LGLEVQKKKE KKQKKKKGKN VDDLKQELDL
70 80 90 100 110 120
EDHKLSIEEL EAKYETSLQG LTSARAAEIL ARDGPNTLTP PKGTPEIIKF LKQMIGGFSL
130 140 150 160 170 180
LLWAGAILCW IAYGILYAQD HNTSRDNLYL GIVLAVVVIL TGCFAYFQEA KSTNIMASFN
190 200 210 220 230 240
QMIPQQAVVT RNGQKLEIPA KDLVVGDLVD VKGGDRIPAD LRIIFAQGCK VDNSSLTGES
250 260 270 280 290 300
EAQPRSSEFT HENPLETKNI AFYSTTCLEG TARGFVINTG DQTIIGRIAS LASGVGNEKT
310 320 330 340 350 360
PIAVEIEHFV HIVAGVAVSV GVLFFIIAIC MGYSALNSII FLIGIIVANV PEGLLATVTV
370 380 390 400 410 420
TLSLTAKRMA KKNCLVKNLE AVETLGSTSI ICSDKTGTLT QNRMTVAHLW FDDHIHIADT
430 440 450 460 470 480
SEDQSHHSFE QTPETWNALC KIVSLCNRAE FKAGQDDVPI MKKVAVGDAS ETALLKFSEV
490 500 510 520 530 540
ITGNVMNIRS QNRKVCEIPF NSTNKFQLSI HETDDPQDQR LLLVMKGAPE RILEKCSTIM
550 560 570 580 590 600
IGGKELPLDE SMKDSFQTAY MELGGLGERV LGFCHLYLPE EEYPSSYAFD IESMNFPTSN
610 620 630 640 650 660
LCFVGLLSMI DPPRSTVPDA VTKCRSAGIK VIMVTGDHPI TAKAIARSVG IISAGSETVD
670 680 690 700 710 720
DIAKRLNIPV EQVNKREAKA AVVNGGELKD MSSEELDDIL TNHAEIVFAR TSPQQKLIIV
730 740 750 760 770 780
EGCQRQNYVV AVTGDGVNDS PALKKADIGI AMGIAGSDAA KNAADMILLD DNFASIVTGV
790 800 810 820 830 840
EEGRLIFDNI KKSIGYTLTK NVAELCPFLI YIIADIPLPI GTITILFIDL GTDIIPSVSF
850 860 870 880 890 900
AYEKAERDIM NRKPRRKNVD RLVNQQLALY AYLQIGIIQS VGAFLNYFTV MAEQGFLPHT
910 920 930 940 950 960
LVGIRIDWEK INNQDLEDSY GQEWTFSQRQ FLEWTGYTAF FVSIVVEQLA DLIIRKTRRN
970 980 990 1000 1010 1020
SVFQQGLFRN KFLLMGLASQ VIIAAFLSYC PEMPYALKFT PLRAQYWFVA APYALLIFVY
1030 1040
DEIRKLFIRR YPGSWWDKNM YY