| anterior/posterior pattern specification |
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. |
| apical protein localization |
Any process in which a protein is transported to, or maintained in, apical regions of the cell. |
| branching involved in blood vessel morphogenesis |
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. |
| cardiac vascular smooth muscle cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers. |
| cell migration involved in kidney development |
The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. |
| cochlea development |
The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. |
| cochlea morphogenesis |
The process in which the cochlea is generated and organized. |
| convergent extension involved in axis elongation |
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism. |
| convergent extension involved in neural plate elongation |
The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate. |
| convergent extension involved in organogenesis |
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ. |
| digestive tract morphogenesis |
The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. |
| dopaminergic neuron axon guidance |
The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues. |
| epicardial cell to mesenchymal cell transition |
A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium. |
| establishment of body hair planar orientation |
Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface. |
| establishment of epithelial cell polarity |
The specification and formation of anisotropic intracellular organization of an epithelial cell. |
| establishment of planar polarity |
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates. |
| establishment of planar polarity involved in neural tube closure |
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. |
| establishment or maintenance of epithelial cell apical/basal polarity |
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell. |
| glomerulus development |
The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. |
| hair follicle development |
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open. |
| heart looping |
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation. |
| heparan sulfate proteoglycan biosynthetic process |
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. |
| inner ear receptor cell development |
The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. |
| inner ear receptor cell stereocilium organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells. |
| kidney morphogenesis |
Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. |
| lateral sprouting involved in lung morphogenesis |
The process in which a branch forms along the side of the lung epithelial tube. |
| membranous septum morphogenesis |
The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. |
| muscular septum morphogenesis |
The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. |
| neural tube closure |
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. |
| non-canonical Wnt signaling pathway |
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin. |
| non-motile cilium assembly |
The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. |
| orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis |
The process in which a lung bud bifurcates perpendicular to the plane of the previous bud. |
| outflow tract septum morphogenesis |
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. |
| planar cell polarity pathway involved in axis elongation |
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation. |
| planar cell polarity pathway involved in axon guidance |
Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance. |
| planar cell polarity pathway involved in heart morphogenesis |
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart. |
| planar cell polarity pathway involved in neural tube closure |
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure. |
| planar dichotomous subdivision of terminal units involved in lung branching morphogenesis |
The process in which a lung bud bifurcates parallel to the plane of the previous bud. |
| positive regulation of JUN kinase activity |
Any process that activates or increases the frequency, rate or extent of JUN kinase activity. |
| post-anal tail morphogenesis |
The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. |
| regulation of actin cytoskeleton organization |
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
| regulation of establishment of planar polarity |
Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. |
| regulation of Wnt signaling pathway |
Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway. |
| Rho protein signal transduction |
The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. |
| serotonergic neuron axon guidance |
The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues. |
| somatic stem cell division |
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. |
| somatic stem cell population maintenance |
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
| Wnt signaling pathway, planar cell polarity pathway |
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity. |
| wound healing |
The series of events that restore integrity to a damaged tissue, following an injury. |
