Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q91XA2

Entry ID Method Resolution Chain Position Source
AF-Q91XA2-F1 Predicted AlphaFoldDB

31 variants for Q91XA2

Variant ID(s) Position Change Description Diseaes Association Provenance
rs30250600 26 I>V No EVA
rs3389295364 47 V>I No EVA
rs216264453 83 R>K No EVA
rs3389215395 128 Q>* No EVA
rs3389295323 136 Q>H No EVA
rs3389283312 136 Q>R No EVA
rs3389255100 141 F>I No EVA
rs3389289964 142 Q>R No EVA
rs3389295362 145 Q>H No EVA
rs30251185 182 N>D No EVA
rs30251186 197 H>R No EVA
rs30250149 201 L>V No EVA
rs3389285994 221 K>R No EVA
rs3389281329 242 K>M No EVA
rs30250150 244 Q>H No EVA
rs3389298076 270 V>SDG* No EVA
rs3389288112 271 A>V No EVA
rs1134813102 275 R>W No EVA
rs29516776 287 L>V No EVA
rs3389289908 301 Y>* No EVA
rs3389245799 311 D>E No EVA
rs264737334 317 R>L No EVA
rs29618849 319 S>A No EVA
rs3389245808 355 N>D No EVA
rs30251040 368 I>V No EVA
rs3389245774 371 V>SDG* No EVA
rs30251041 373 V>D No EVA
rs1132820843 376 E>G No EVA
rs30251042 379 S>N No EVA
rs30251043 389 I>V No EVA
rs3389289919 392 Q>* No EVA

No associated diseases with Q91XA2

No regional properties for Q91XA2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q91XA2

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus, cis-Golgi network membrane ; Single-pass type II membrane protein
  • Early Golgi
  • Cycles via the cell surface and endosomes upon lumenal pH disruption
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
nucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMGLGNGRRS MKSPPLILAA LVACVIVLGF NYWIASSRSV ELQTRIVELE GRVRRAAAER
70 80 90 100 110 120
GAVELKKNEF QGELQKQREQ LDRIQSSHSF QLENVNKLHQ DEKAVLVNNI TTGEKLIRDL
130 140 150 160 170 180
QDQLKALQRS YSSLQQDIFQ FQKNQTSLEK KFSYDLNQCI SQMTEVKEQC DERIEEVIRK
190 200 210 220 230 240
RNEAPGSRDL AETNNQHQQA LKPQPKLQEE VPSEEQMPQE KGDVPRNKSQ IPAPNSESLG
250 260 270 280 290 300
LKPQVQNEET NEIQAVGEEH QQASIQGQAV ADGTRVGAEK LDQHTQLPAG LLARPEEDSQ
310 320 330 340 350 360
YPEREQLVIR DRQEQQRASE EGGGQKNPGD EYDMDENEAE SEREKQAALA GNDRNINVLN
370 380 390
ADAQKRGIIN VPVGSERQSH ILNQVGIHIP QQA