Q91903

PR
Gene name
elavl2
Protein name
ELAV-like protein 2
Names
Elav like-1, Xel-1, Protein ElrB, p45
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:394342
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-94 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q91903

Entry ID Method Resolution Chain Position Source
AF-Q91903-F1 Predicted AlphaFoldDB

No variants for Q91903

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q91903

No associated diseases with Q91903

5 regional properties for Q91903

Type Name Position InterPro Accession
domain RNA recognition motif domain 66 - 145 IPR000504-1
domain RNA recognition motif domain 153 - 233 IPR000504-2
domain RNA recognition motif domain 306 - 384 IPR000504-3
domain HuB, RNA recognition motif 3 303 - 388 IPR034914
domain HuB, RNA recognition motif 2 148 - 231 IPR034999

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasm, cell cortex
  • Enriched at the vegetal cortex in stage III and IV oocytes
  • Shows both nuclear and cytoplasmic localization in the neural tube at the neurula stage, although endogenous elavl2 is not expressed at this stage
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cell cortex The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

3 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.
mRNA 3'-UTR binding Binding to a 3' untranslated region of an mRNA molecule.
uridine-rich cytoplasmic polyadenylylation element binding Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.

4 GO annotations of biological process

Name Definition
intracellular mRNA localization Any process in which mRNA is transported to, or maintained in, a specific location within the cell.
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
negative regulation of transcription by RNA polymerase II Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
nervous system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAVRLCDVAS LLRSGSWAAE PWTGQVIAAM ETQLSNGPTC NNTANCPNTI NCSSPVESNN
70 80 90 100 110 120
TEDSKTNLIV NYLPQNMTQE ELKSLFGSIG EIESCKLVRD KITEGQSLGY GFVNYIDPKD
130 140 150 160 170 180
AEKAINTLNG LRLQTKTIKV SYARPSSASI RDANLYVSGL PKTMTQKELE QLFSQYGRII
190 200 210 220 230 240
TSRILVDQVT GVSRGVGFIR FDKRIEAEEA IKGLNGQKPP GATEPITVKF ANNPSQKVNH
250 260 270 280 290 300
TILSQLYQSP NRRYPGPLAQ QAQRFRLDNL LNMAYGGIKS RFSPMAIDGM TSLAGINFPG
310 320 330 340 350 360
HAGTGWCIFV YNLAPDADES ILWQMFGPFG AVTNVKVIRD FNTNKCKGFG FVTMTNYDEA
370 380
AMAIASLNGY RLGDRVLQVS FKTSKTHKA