Q91848

PR
Gene name
siamois
Protein name
Homeobox protein siamois
Names
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:378613
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

72-246 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q91848

Entry ID Method Resolution Chain Position Source
AF-Q91848-F1 Predicted AlphaFoldDB

No variants for Q91848

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q91848

No associated diseases with Q91848

1 regional properties for Q91848

Type Name Position InterPro Accession
domain Homeobox domain 140 - 204 IPR001356

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
transcription regulator complex A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.

1 GO annotations of molecular function

Name Definition
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

7 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
mesoderm formation The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
nervous system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Spemann organizer formation at the dorsal lip of the blastopore Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.
Wnt signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTYEAEMEQI VSTALTLQDD YIKFTPRNQN MACHAEIIGI FHDIHPTVEI KEPHQDKSVL
70 80 90 100 110 120
QETLVELYSV LGIPQEPQVS KTMKFEEPEQ HKESSSTVTR SDSLVNSLQS TGLKRPFCED
130 140 150 160 170 180
EHREYKKPLI QAEDISPATS TRSRKRTIYS KEQTNFLQNQ FDLNPYPDFV NRCRIAKITG
190 200 210 220 230 240
IPEPRIQVWF QNRRARHLPR ATTFHSPQGR KSPTSEGPRS FLSREAHYPD EWGQAPNPSN
TQPYPN