Q91813

PR
Gene name
otx2-a
Protein name
Homeobox protein OTX2-A
Names
xOTX2-A, Orthodenticle 2-A, Orthodenticle-A-like protein A
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:399342
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-63 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q91813

Entry ID Method Resolution Chain Position Source
AF-Q91813-F1 Predicted AlphaFoldDB

No variants for Q91813

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q91813

No associated diseases with Q91813

No regional properties for Q91813

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q91813

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

1 GO annotations of biological process

Name Definition
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMSYLKQPPY AVNGLSLTAS GMDLLHQSVG YPATPRKQRR ERTTFTRAQL DILEALFAKT
70 80 90 100 110 120
RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQQQ QNGGQNKVRP SKKKTSPVRE
130 140 150 160 170 180
VSSESGTSGQ FSPPSSTSVP VISSSTAPVS IWSPASVSPL SDPLSTSSSC MQRSYPMTYT
190 200 210 220 230 240
QASGYSQGYA GSTSYFGGMD CGSYLSPMHH QLSGPGATLS PMGTNAVTSH LNQSPVALSS
250 260 270 280
QAYGASSLGF NSTDCLDYKD QTASWKLNFN ADCLDYKDQT SSWKFQVL