Q91712

PR
Gene name
ets2-b
Protein name
Protein c-ets-2-B
Names
C-ets-2B
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

21-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q91712

Entry ID Method Resolution Chain Position Source
AF-Q91712-F1 Predicted AlphaFoldDB

No variants for Q91712

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q91712

No associated diseases with Q91712

3 regional properties for Q91712

Type Name Position InterPro Accession
domain Ets domain 365 - 450 IPR000418
domain Pointed domain 85 - 170 IPR003118
domain Ets1, N-terminal flanking region of Ets domain 263 - 362 IPR045688

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEFGIRNMD QVAPVYNGHR GMLKRQLAFD NVQVPTSLYC GLFSAYEEEQ AVPTGLDSYP
70 80 90 100 110 120
HDSSSCELPL LTPCSKAVMS QALKDTFNGF AKERCRLGIP GNPWLWDENN VLQWLLWAAK
130 140 150 160 170 180
EFSLENVNFQ KFLMNGHELC SLGKERFLAL APDFVGDILW EHLEEMMKEY QEKAQEPYID
190 200 210 220 230 240
HSNRDSLNQW MNADSLNFTA DPLQCGAQVH NYPKNGMYND MCSVPTGQTL LNPKQEFQQY
250 260 270 280 290 300
PSSCLKSRAV NYPPASQDFA RSHMNVLLNS LNSGKLRDYD SGDSGTESFE STESLLHSWT
310 320 330 340 350 360
SQSSLVDMQR VPSYDSFEED GNQTLCLNKQ PMSFKDYIQD RCEPAELGKP VIPASILAGF
370 380 390 400 410 420
TGSGPIQLWQ FLLELLTDKS CQSFISWTGD GWEFKLADPD EVARRWGKRK NKPKMNYEKL
430 440 450 460 470
SRGLRYYYDK NIIHKTSGKR YVYRFVCDLH NLLGYTPDEL HAMLGVQPDT DE