| bone development |
The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. |
| cartilage condensation |
The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes. |
| cartilage development |
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. |
| cell adhesion |
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. |
| chondrocyte development |
The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. |
| embryonic skeletal system development |
The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. |
| esophagus smooth muscle contraction |
A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract. |
| glial cell-derived neurotrophic factor receptor signaling pathway |
The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor. |
| heparan sulfate proteoglycan metabolic process |
The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. |
| innervation |
The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue. |
| kidney development |
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. |
| limb joint morphogenesis |
The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. |
| negative regulation of angiogenesis |
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. |
| negative regulation of cell migration |
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. |
| negative regulation of endothelial cell proliferation |
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. |
| negative regulation of fibroblast growth factor receptor signaling pathway |
Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. |
| negative regulation of prostatic bud formation |
Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. |
| positive regulation of BMP signaling pathway |
Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity. |
| positive regulation of canonical Wnt signaling pathway |
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. |
| positive regulation of smooth muscle cell proliferation |
Any process that activates or increases the rate or extent of smooth muscle cell proliferation. |
| positive regulation of Wnt signaling pathway |
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction. |
| vascular endothelial growth factor receptor signaling pathway |
The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
